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Standards Ontologies Notations
Alzheimer's disease

Summary
Synonym
  • Alzheimer disease
  • Alzheimers dementia
Definition
A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Super Class
tauopathy
External Links
Disease Ontology
DOID:10652
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 261 - 270 of 350 in total
Gene ID Gene Symbol Description Source
9791 PTDSS1 phosphatidylserine synthase 1
9957 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1
10005 ACOT8 acyl-CoA thioesterase 8
10020 GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
10082 GPC6 glypican 6
10135 NAMPT nicotinamide phosphoribosyltransferase
10195 ALG3 ALG3 alpha-1,3- mannosyltransferase
10327 AKR1A1 aldo-keto reductase family 1 member A1
10400 PEMT phosphatidylethanolamine N-methyltransferase
10457 GPNMB glycoprotein nmb
Displaying entries 1 - 10 of 24 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11815 Apod apolipoprotein D
12015 Bad BCL2-associated agonist of cell death
13806 Eno1 enolase 1, alpha non-neuron
14433 Gapdh glyceraldehyde-3-phosphate dehydrogenase
14447 Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
14526 Gcg glucagon
14873 Gsto1 glutathione S-transferase omega 1
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
16002 Igf2 insulin-like growth factor 2
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
24333 Eno1 enolase 1
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24835 Tnf tumor necrosis factor
25239 Apod apolipoprotein D
25513 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25608 Lep leptin
Displaying all 9 entries
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
33351 Eno Enolase
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
37131 Pepck1 Phosphoenolpyruvate carboxykinase 1
38973 se sepia
43222 Tl Toll
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
406367 gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
560788 parp1 poly (ADP-ribose) polymerase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
380259 gapdh.S glyceraldehyde-3-phosphate dehydrogenase S homeolog Xenopus laevis (African clawed frog)
380298 eno1.S enolase 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
174423 enol-1 Enolase
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
183000 gsto-1 Glutathione transferase omega-1
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying all 9 entries
Gene ID Gene Symbol Description Source
850666 GTT2 glutathione transferase GTT2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853169 ENO1 phosphopyruvate hydratase ENO1
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854575 ERR1 phosphopyruvate hydratase ERR1
855373 ERR3 phosphopyruvate hydratase ERR3
855848 ERR2 phosphopyruvate hydratase ERR2
856579 ENO2 phosphopyruvate hydratase ENO2
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024