granulomatosis with polyangiitis

Summary
Synonym
  • Necrotizing respiratory granulomatosis
  • Wegener granulomatosis, formerly
Definition
An autoimmune disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.
Super Class
autoimmune disease of blood kidney disease lung disease skin disease
External Links
Disease Ontology
DOID:12132
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entry 21 - 21 of 21 in total
Gene ID Gene Symbol Description Source
100507436 MICA MHC class I polypeptide-related sequence A

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024