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Chagas disease
Summary
- Synonym
-
- Chagas' disease
- chagas' disease with digestive system involvement
- chagas' disease with nervous system involvement
- chagas' disease with other organ involvement
- Definition
- A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
- Super Class
- trypanosomiasis
External Links
- Disease Ontology
- DOID:12140
- Mondo Disease Ontology
- MeSH
- UMLS
- ORDO
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5291 | PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | |
| 5293 | PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | |
| 5294 | PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | |
| 5332 | PLCB4 | phospholipase C beta 4 | |
| 5553 | PRG2 | proteoglycan 2, pro eosinophil major basic protein | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 6385 | SDC4 | syndecan 4 | |
| 6609 | SMPD1 | sphingomyelin phosphodiesterase 1 | |
| 6646 | SOAT1 | sterol O-acyltransferase 1 | |
| 7167 | TPI1 | triosephosphate isomerase 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P49247 | Ribose-5-phosphate isomerase | |
| P60174 | Triosephosphate isomerase | |
| Q15147 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 | |
| Q15485 | Ficolin-2 | |
| Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 |
