Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Related Genes
Displaying entries 1 - 10 of 180 in total
Gene ID Gene Symbol Description Source
2 A2M alpha-2-macroglobulin
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
111 ADCY5 adenylate cyclase 5
131 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
157 GRK3 G protein-coupled receptor kinase 3
185 AGTR1 angiotensin II receptor type 1
207 AKT1 AKT serine/threonine kinase 1
Displaying entries 101 - 110 of 146 in total
Gene ID Gene Symbol Description Source
56458 Foxo1 forkhead box O1
56637 Gsk3b glycogen synthase kinase 3 beta
57320 Park7 Parkinson disease (autosomal recessive, early onset) 7
67264 Ndufb8 NADH:ubiquinone oxidoreductase subunit B8
67971 Tppp3 tubulin polymerization-promoting protein family member 3
68214 Gsto2 glutathione S-transferase omega 2
72685 Dnajc6 DnaJ heat shock protein family (Hsp40) member C6
72948 Tppp tubulin polymerization promoting protein
72961 Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
73316 Calr3 calreticulin 3
Displaying entries 31 - 40 of 82 in total
Gene ID Gene Symbol Description Source
25715 Slc11a2 solute carrier family 11 member 2
25718 Igf1r insulin-like growth factor 1 receptor
26201 ND4 NADH dehydrogenase subunit 4
29143 Grn granulin precursor
29219 Snca synuclein alpha
29237 Penk proenkephalin
29238 Drd3 dopamine receptor D3
29256 Oprl1 opioid related nociceptin receptor 1
29335 Oprk1 opioid receptor, kappa 1
29414 Akt3 AKT serine/threonine kinase 3
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
37196 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A
37455 Egfr Epidermal growth factor receptor
38545 nAChRbeta1 nicotinic Acetylcholine Receptor beta1
39557 Hsp110 Heat shock protein 110
41166 Calr Calreticulin
41625 Ace Acetylcholine esterase
41726 Dop1R1 Dopamine 1-like receptor 1
41840 Hsc70-4 Heat shock protein 70 cognate 4
42490 Mvl Malvolio
42549 InR Insulin-like receptor
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1

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Last updated: December 9, 2024