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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 121 - 130 of 180 in total
Gene ID Gene Symbol Description Source
8398 PLA2G6 phospholipase A2 group VI
8643 PTCH2 patched 2
8672 EIF4G3 eukaryotic translation initiation factor 4 gamma 3
8867 SYNJ1 synaptojanin 1
8871 SYNJ2 synaptojanin 2
9446 GSTO1 glutathione S-transferase omega 1
9554 SEC22B SEC22 homolog B, vesicle trafficking protein
9749 PHACTR2 phosphatase and actin regulator 2
9789 SPCS2 signal peptidase complex subunit 2
10000 AKT3 AKT serine/threonine kinase 3
Displaying entries 51 - 60 of 146 in total
Gene ID Gene Symbol Description Source
16337 Insr insulin receptor
16846 Lep leptin
17762 Mapt microtubule-associated protein tau
18039 Nefl neurofilament, light polypeptide
18053 Ngfr nerve growth factor receptor (TNFR superfamily, member 16)
18174 Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
18195 Nsf N-ethylmaleimide sensitive fusion protein
18216 Ntsr1 neurotensin receptor 1
18294 Ogg1 8-oxoguanine DNA-glycosylase 1
18386 Oprd1 opioid receptor, delta 1
Displaying entries 1 - 10 of 82 in total
Gene ID Gene Symbol Description Source
24153 A2m alpha-2-macroglobulin
24180 Agtr1a angiotensin II receptor, type 1a
24185 Akt1 AKT serine/threonine kinase 1
24225 Bdnf brain-derived neurotrophic factor
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24318 Drd2 dopamine receptor D2
24335 Epo erythropoietin
24473 Htr1a 5-hydroxytryptamine receptor 1A
24483 Igf2 insulin-like growth factor 2
24596 Ngfr nerve growth factor receptor
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
42803 Hmgcr HMG Coenzyme A reductase
42918 nAChRalpha1 nicotinic Acetylcholine Receptor alpha1
42920 nAChRbeta2 nicotinic Acetylcholine Receptor beta2
43565 Axn Axin
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850721 SMF3 putative divalent metal ion transporter SMF3
851013 ACO1 aconitate hydratase ACO1
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852351 AKL1 serine/threonine protein kinase AKL1
852470 SMY2 Smy2p
852495 PGI1 glucose-6-phosphate isomerase
852806 HSF1 stress-responsive transcription factor HSF1
853071 TIF4631 translation initiation factor eIF4G
853300 YAK1 serine/threonine protein kinase YAK1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024