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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Parkinson's disease
Summary
- Synonym
-
- Parkinson disease
- paralysis agitans
- Definition
- A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
- Super Class
- synucleinopathy
External Links
- Disease Ontology
- DOID:14330
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
- MGI genotype (from TogoID)
-
- 5756630
- 5462366
- 5471363
- 5471365
- 5512702
- 5544078
- 5573199
- 5604250
- 5604280
- 5647883
- 5447073
- 5775427
- 6099056
- 6099058
- 6113412
- 6113542
- 6113543
- 6489606
- 6852560
- 7378801
- 3815302
- 2675764
- 3038236
- 3619915
- 3702932
- 3712364
- 3764817
- 3764818
- 3765154
- 3774594
- 2662300
- 3839946
- 4429423
- 4429667
- 4936868
- 5014212
- 5049966
- 5316006
- 5432013
- 5441517
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2 | A2M | alpha-2-macroglobulin | |
| 25 | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | |
| 43 | ACHE | acetylcholinesterase (Yt blood group) | |
| 50 | ACO2 | aconitase 2 | |
| 111 | ADCY5 | adenylate cyclase 5 | |
| 131 | ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | |
| 142 | PARP1 | poly(ADP-ribose) polymerase 1 | |
| 157 | GRK3 | G protein-coupled receptor kinase 3 | |
| 185 | AGTR1 | angiotensin II receptor type 1 | |
| 207 | AKT1 | AKT serine/threonine kinase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 56458 | Foxo1 | forkhead box O1 | |
| 56637 | Gsk3b | glycogen synthase kinase 3 beta | |
| 57320 | Park7 | Parkinson disease (autosomal recessive, early onset) 7 | |
| 67264 | Ndufb8 | NADH:ubiquinone oxidoreductase subunit B8 | |
| 67971 | Tppp3 | tubulin polymerization-promoting protein family member 3 | |
| 68214 | Gsto2 | glutathione S-transferase omega 2 | |
| 72685 | Dnajc6 | DnaJ heat shock protein family (Hsp40) member C6 | |
| 72948 | Tppp | tubulin polymerization promoting protein | |
| 72961 | Slc17a7 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 | |
| 73316 | Calr3 | calreticulin 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 113893 | Sncb | synuclein, beta | |
| 114114 | Dnm1l | dynamin 1-like | |
| 114243 | Nox1 | NADPH oxidase 1 | |
| 114245 | Hcn3 | hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 | |
| 116660 | Ptprn | protein tyrosine phosphatase, receptor type, N | |
| 117064 | Vip | vasoactive intestinal peptide | |
| 117549 | Gpr37 | G protein-coupled receptor 37 | |
| 157074 | Sdha | succinate dehydrogenase complex flavoprotein subunit A | |
| 171044 | Sstr3 | somatostatin receptor 3 | |
| 171131 | Chrnb3 | cholinergic receptor nicotinic beta 3 subunit |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 42803 | Hmgcr | HMG Coenzyme A reductase | |
| 42918 | nAChRalpha1 | nicotinic Acetylcholine Receptor alpha1 | |
| 42920 | nAChRbeta2 | nicotinic Acetylcholine Receptor beta2 | |
| 43565 | Axn | Axin | |
| 3355109 | Parp1 | Poly-(ADP-ribose) polymerase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 436629 | nus1 | NUS1 dehydrodolichyl diphosphate synthase subunit | |
| 437021 | tspan36 | tetraspanin 36 | |
| 494492 | slc17a6a | solute carrier family 17 member 6a | |
| 560788 | parp1 | poly (ADP-ribose) polymerase 1 | |
| 563467 | slc17a8 | solute carrier family 17 member 8 | |
| 768121 | foxo1a | forkhead box O1 a | |
| 100004455 | epoa | erythropoietin a | |
| 100149756 | slc17a6b | solute carrier family 17 member 6b |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 398022 | igf1r.S | insulin like growth factor 1 receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 398763 | agtr1.L | angiotensin II receptor type 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 399170 | akt1.S | AKT serine/threonine kinase 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) | |
| 780064 | slc17a7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | Xenopus tropicalis (tropical clawed frog) | |
| 108705891 | drd5.S | dopamine receptor D5 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171965 | pgk-1 | putative phosphoglycerate kinase | |
| 172105 | unc-38 | Acetylcholine receptor subunit alpha-type unc-38 | |
| 172150 | unc-63 | Acetylcholine receptor subunit alpha-type unc-63 | |
| 173574 | gba-1 | Putative glucosylceramidase 1 | |
| 174274 | ptc-1 | Protein patched homolog 1;SSD domain-containing protein | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175076 | ace-3 | Carboxylic ester hydrolase | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175807 | ida-1 | Receptor-type tyrosine-protein phosphatase-like ida-1 | |
| 176291 | eat-4 | Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850370 | PGK1 | phosphoglycerate kinase | |
| 850721 | SMF3 | putative divalent metal ion transporter SMF3 | |
| 851013 | ACO1 | aconitate hydratase ACO1 | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 852351 | AKL1 | serine/threonine protein kinase AKL1 | |
| 852470 | SMY2 | Smy2p | |
| 852495 | PGI1 | glucose-6-phosphate isomerase | |
| 852806 | HSF1 | stress-responsive transcription factor HSF1 | |
| 853071 | TIF4631 | translation initiation factor eIF4G | |
| 853300 | YAK1 | serine/threonine protein kinase YAK1 |
