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myelofibrosis
Summary
- Synonym
-
- Agnogenic myeloid metaplasia
- Aleukemic myelosis
- Megakaryocytic myelosclerosis
- bone Marrow Fibrosis
- myelosclerosis
- primary myelofibrosis
- Definition
- A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.
- Super Class
- myeloid neoplasm
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5293 | PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | |
| 5294 | PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | |
| 5553 | PRG2 | proteoglycan 2, pro eosinophil major basic protein | |
| 6403 | SELP | selectin P | |
| 6646 | SOAT1 | sterol O-acyltransferase 1 | |
| 6916 | TBXAS1 | thromboxane A synthase 1 | |
| 7157 | TP53 | tumor protein p53 | |
| 8809 | IL18R1 | interleukin 18 receptor 1 | |
| 57126 | CD177 | CD177 molecule | |
| 158326 | FREM1 | FRAS1 related extracellular matrix 1 |
Related Glycoprotein
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001876 | Pancytopenia |
| HP:0012378 | Fatigue |
| HP:0001945 | Fever |
| HP:0001433 | Hepatosplenomegaly |
| HP:0004326 | Cachexia |
| HP:0000967 | Petechiae |
| HP:0001974 | Leukocytosis |
| HP:0004377 | Hematological neoplasm |
| HP:0001744 | Splenomegaly |
| HP:0005561 | Abnormal bone marrow cell morphology |
