obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 343 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
51 ACOX1 acyl-CoA oxidase 1
123 PLIN2 perilipin 2
133 ADM adrenomedullin
134 ADORA1 adenosine A1 receptor
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
Displaying entries 51 - 60 of 241 in total
Gene ID Gene Symbol Description Source
13488 Drd1 dopamine receptor D1
13489 Drd2 dopamine receptor D2
13491 Drd4 dopamine receptor D4
13982 Esr1 estrogen receptor 1 (alpha)
13983 Esr2 estrogen receptor 2 (beta)
14061 F2 coagulation factor II
14068 F7 coagulation factor VII
14081 Acsl1 acyl-CoA synthetase long-chain family member 1
14182 Fgfr1 fibroblast growth factor receptor 1
14221 Fjx1 four jointed box 1
Displaying entries 1 - 10 of 151 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24217 Atp4b ATPase H+/K+ transporting subunit beta
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24267 Comt catechol-O-methyltransferase
24310 Ace angiotensin I converting enzyme
24318 Drd2 dopamine receptor D2
24367 Fgg fibrinogen gamma chain
24377 G6pd glucose-6-phosphate dehydrogenase
Displaying entries 31 - 40 of 43 in total
Gene ID Gene Symbol Description Source
39435 Tsf2 Transferrin 2
41549 Octbeta2R Octopamine beta2 receptor
41713 PK1-R Pyrokinin 1 receptor
41726 Dop1R1 Dopamine 1-like receptor 1
42160 htl heartless
42514 Snmp1 Sensory neuron membrane protein 1
42549 InR Insulin-like receptor
42652 Octbeta1R Octopamine beta1 receptor
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 11 - 20 of 51 in total
Gene ID Gene Symbol Description Source
176124 npr-17 putative G-protein coupled receptor C06G4.5
176286 glp-1 glp-1/Notch intracellular domain
176304 dat-1 Sodium-dependent dopamine transporter
176390 cnx-1 Calnexin
176852 dsc-4 Microsomal triglyceride transfer protein homolog
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
177372 cpi-1 Cystatin cpi-1
177597 rig-4 Protein sidekick homolog
177668 C49C8.5 Fibrinogen C-terminal domain-containing protein
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024