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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
obesity
Summary
- Definition
- An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
- Super Class
- overnutrition
External Links
- Disease Ontology
- DOID:9970
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
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- 3766125
- 3821619
- 3821616
- 3817475
- 3799316
- 3784993
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- 3773447
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- 3721145
- 3715252
- 3694548
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- 3655835
- 5515728
- 7545554
- 7545550
- 7545546
- 6273993
- 5828524
- 5766495
- 5763310
- 5763241
- 3655832
- 5447549
- 5300906
- 3850836
- 3847120
- 3840234
- 3832410
- 3822318
- 3033164
- 3511746
- 3055585
- 3055584
- 3053798
- 3041643
- 3036853
- 3036852
- 3033165
- 3511747
- 2681522
- 2680503
- 2669229
- 2663736
- 2654708
- 2653295
- 2651886
- 2388265
- 3589409
- 3655811
- 3639781
- 3639355
- 3639354
- 3629805
- 3623749
- 3620067
- 3611807
- 2174793
- 3586756
- 3582615
- 3580003
- 3579026
- 3577766
- 3526863
- 3511748
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2835 | GPR12 | G protein-coupled receptor 12 | |
| 2847 | MCHR1 | melanin concentrating hormone receptor 1 | |
| 2876 | GPX1 | glutathione peroxidase 1 | |
| 2878 | GPX3 | glutathione peroxidase 3 | |
| 2908 | NR3C1 | nuclear receptor subfamily 3 group C member 1 | |
| 2946 | GSTM2 | glutathione S-transferase mu 2 | |
| 2984 | GUCY2C | guanylate cyclase 2C | |
| 3033 | HADH | hydroxyacyl-CoA dehydrogenase | |
| 3077 | HFE | homeostatic iron regulator | |
| 3082 | HGF | hepatocyte growth factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11303 | Abca1 | ATP-binding cassette, sub-family A member 1 | |
| 11421 | Ace | angiotensin I converting enzyme | |
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 11520 | Plin2 | perilipin 2 | |
| 11537 | Cfd | complement factor D | |
| 11539 | Adora1 | adenosine A1 receptor | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11556 | Adrb3 | adrenergic receptor, beta 3 | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 11625 | Ahsg | alpha-2-HS-glycoprotein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 83567 | Mchr1 | melanin-concentrating hormone receptor 1 | |
| 83571 | Cdkn1b | cyclin-dependent kinase inhibitor 1B | |
| 83619 | Nfe2l2 | NFE2 like bZIP transcription factor 2 | |
| 83840 | Rps6kb1 | ribosomal protein S6 kinase B1 | |
| 84022 | Ghsr | growth hormone secretagogue receptor | |
| 84032 | Col3a1 | collagen type III alpha 1 chain | |
| 84349 | Cd40lg | CD40 ligand | |
| 84353 | Ctnnb1 | catenin beta 1 | |
| 85268 | Hrh3 | histamine receptor H3 | |
| 85431 | Nox4 | NADPH oxidase 4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31002 | Appl | beta amyloid protein precursor-like | |
| 31017 | sdk | sidekick | |
| 31234 | Pdfr | Pigment-dispersing factor receptor | |
| 31293 | N | Notch | |
| 32545 | Gapdh2 | Glyceraldehyde 3 phosphate dehydrogenase 2 | |
| 32556 | Stim | Stromal interaction molecule | |
| 32974 | Zw | Zwischenferment | |
| 33007 | Dop2R | Dopamine 2-like receptor | |
| 33245 | ds | dachsous | |
| 33627 | ft | fat |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30128 | wnt1 | wingless-type MMTV integration site family, member 1 | |
| 30308 | wnt10b | wingless-type MMTV integration site family, member 10b | |
| 30686 | myca | MYC proto-oncogene, bHLH transcription factor a | |
| 30705 | fgfr1a | fibroblast growth factor receptor 1a | |
| 30718 | notch1a | notch receptor 1a | |
| 266751 | adra2b | adrenoceptor alpha 2B | |
| 286833 | mc4r | melanocortin 4 receptor | |
| 317743 | gapdh | glyceraldehyde-3-phosphate dehydrogenase | |
| 393141 | mycb | MYC proto-oncogene, bHLH transcription factor b | |
| 406207 | mttp | microsomal triglyceride transfer protein |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373580 | crhr1.2.S | corticotropin releasing hormone receptor 1, gene 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 373759 | cnr1.S | cannabinoid receptor 1 (brain) S homeolog | Xenopus laevis (African clawed frog) | |
| 373802 | pomc.S | proopiomelanocortin S homeolog | Xenopus laevis (African clawed frog) | |
| 378584 | drd2.L | dopamine receptor D2 L homeolog | Xenopus laevis (African clawed frog) | |
| 378693 | npy2r.S | neuropeptide Y receptor Y2 S homeolog | Xenopus laevis (African clawed frog) | |
| 379783 | akt2.L | v-akt murine thymoma viral oncogene homolog 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 380532 | pomc.L | proopiomelanocortin L homeolog | Xenopus laevis (African clawed frog) | |
| 394945 | cfd | complement factor D | Xenopus tropicalis (tropical clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 397782 | fgfr1.S | fibroblast growth factor receptor 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180601 | gpd-3 | Glyceraldehyde-3-phosphate dehydrogenase 3 | |
| 180714 | dop-1 | Dopamine receptor 1 | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180783 | apl-1 | Amyloid-beta-like protein | |
| 180812 | scav-1 | SCAVenger receptor (CD36 family) related | |
| 180836 | W01C8.5 | DM13 domain-containing protein | |
| 181166 | pkc-2 | Protein kinase C;Protein kinase C-like 2 | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 181259 | sdn-1 | Syndecan;putative syndecan | |
| 181494 | nkb-3 | Sodium/potassium-transporting ATPase subunit beta;putative sodium/potassium-transporting ATPase subunit beta-3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850391 | NPP1 | nucleotide diphosphatase/phosphodiesterase NPP1 | |
| 850442 | SRB8 | Srb8p | |
| 850614 | HXK1 | hexokinase 1 | |
| 850647 | PUF3 | mRNA-binding protein PUF3 | |
| 851241 | CNE1 | calnexin | |
| 851888 | DPL1 | sphinganine-1-phosphate aldolase DPL1 | |
| 851974 | YPR1 | trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1 | |
| 852053 | SSN2 | Ssn2p | |
| 852102 | IZH1 | PAQR-type receptor |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0010982 | Polygenic inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0012340 | Decreased resting energy expenditure |
| HP:0001513 | Obesity |
