obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 311 - 320 of 343 in total
Gene ID Gene Symbol Description Source
55818 KDM3A lysine demethylase 3A
56623 INPP5E inositol polyphosphate-5-phosphatase E
56848 SPHK2 sphingosine kinase 2
56923 NMUR2 neuromedin U receptor 2
56999 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9
57104 PNPLA2 patatin like phospholipase domain containing 2
57620 STIM2 stromal interaction molecule 2
57678 GPAM glycerol-3-phosphate acyltransferase, mitochondrial
63892 THADA THADA armadillo repeat containing
64240 ABCG5 ATP binding cassette subfamily G member 5
Displaying entries 1 - 10 of 241 in total
Gene ID Gene Symbol Description Source
11303 Abca1 ATP-binding cassette, sub-family A member 1
11421 Ace angiotensin I converting enzyme
11450 Adipoq adiponectin, C1Q and collagen domain containing
11520 Plin2 perilipin 2
11537 Cfd complement factor D
11539 Adora1 adenosine A1 receptor
11555 Adrb2 adrenergic receptor, beta 2
11556 Adrb3 adrenergic receptor, beta 3
11596 Ager advanced glycosylation end product-specific receptor
11625 Ahsg alpha-2-HS-glycoprotein
Displaying entries 31 - 40 of 151 in total
Gene ID Gene Symbol Description Source
24898 Slc6a3 solute carrier family 6 member 3
25014 Acat1 acetyl-CoA acetyltransferase 1
25023 Prkcb protein kinase C, beta
25024 Gipr gastric inhibitory polypeptide receptor
25051 Glp1r glucagon-like peptide 1 receptor
25058 Hk1 hexokinase 1
25059 Hk2 hexokinase 2
25075 Htr1b 5-hydroxytryptamine receptor 1B
25085 Th tyrosine hydroxylase
25116 Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31017 sdk sidekick
31234 Pdfr Pigment-dispersing factor receptor
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32556 Stim Stromal interaction molecule
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33245 ds dachsous
33627 ft fat
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 31 - 40 of 51 in total
Gene ID Gene Symbol Description Source
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
180714 dop-1 Dopamine receptor 1
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
180783 apl-1 Amyloid-beta-like protein
180812 scav-1 SCAVenger receptor (CD36 family) related
180836 W01C8.5 DM13 domain-containing protein
181166 pkc-2 Protein kinase C;Protein kinase C-like 2
181178 gpx-5 Glutathione peroxidase
181259 sdn-1 Syndecan;putative syndecan
181494 nkb-3 Sodium/potassium-transporting ATPase subunit beta;putative sodium/potassium-transporting ATPase subunit beta-3
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024