obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 1 - 10 of 343 in total
Gene ID Gene Symbol Description Source
19 ABCA1 ATP binding cassette subfamily A member 1
32 ACACB acetyl-CoA carboxylase beta
38 ACAT1 acetyl-CoA acetyltransferase 1
51 ACOX1 acyl-CoA oxidase 1
123 PLIN2 perilipin 2
133 ADM adrenomedullin
134 ADORA1 adenosine A1 receptor
154 ADRB2 adrenoceptor beta 2
155 ADRB3 adrenoceptor beta 3
177 AGER advanced glycosylation end-product specific receptor
Displaying entries 171 - 180 of 241 in total
Gene ID Gene Symbol Description Source
21939 Cd40 CD40 antigen
21947 Cd40lg CD40 ligand
22041 Trf transferrin
22157 Tulp1 TUB like protein 1
22228 Ucp2 uncoupling protein 2 (mitochondrial, proton carrier)
22371 Vwf Von Willebrand factor
22408 Wnt1 wingless-type MMTV integration site family, member 1
22410 Wnt10b wingless-type MMTV integration site family, member 10B
26383 Fto FTO alpha-ketoglutarate dependent dioxygenase
27409 Abcg5 ATP binding cassette subfamily G member 5
Displaying entry 151 - 151 of 151 in total
Gene ID Gene Symbol Description Source
690163 Oxct1 3-oxoacid CoA transferase 1
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31017 sdk sidekick
31234 Pdfr Pigment-dispersing factor receptor
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32556 Stim Stromal interaction molecule
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33245 ds dachsous
33627 ft fat
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 41 - 50 of 51 in total
Gene ID Gene Symbol Description Source
181684 cpd-2 Peptidase M14 carboxypeptidase A domain-containing protein
181708 let-2 Collagen alpha-2(IV) chain
181720 C06G1.1 Lipid-binding serum glycoprotein C-terminal domain-containing protein
181723 hda-4 Histone deacetylase 4
182513 gpx-3 Glutathione peroxidase 3
182726 nkb-1 Sodium/potassium-transporting ATPase subunit beta-1
183811 nhx-3 putative Na(+)/H(+) antiporter nhx-3
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9
191374 dhrr-1 G_PROTEIN_RECEP_F2_4 domain-containing protein
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024