obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 81 - 90 of 343 in total
Gene ID Gene Symbol Description Source
2155 F7 coagulation factor VII
2180 ACSL1 acyl-CoA synthetase long chain family member 1
2260 FGFR1 fibroblast growth factor receptor 1
2266 FGG fibrinogen gamma chain
2309 FOXO3 forkhead box O3
2475 MTOR mechanistic target of rapamycin kinase
2539 G6PD glucose-6-phosphate dehydrogenase
2559 GABRA6 gamma-aminobutyric acid type A receptor subunit alpha6
2587 GALR1 galanin receptor 1
2597 GAPDH glyceraldehyde-3-phosphate dehydrogenase
Displaying entries 131 - 140 of 241 in total
Gene ID Gene Symbol Description Source
18654 Pgf placental growth factor
18708 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
18751 Prkcb protein kinase C, beta
18759 Prkci protein kinase C, iota
18791 Plat plasminogen activator, tissue
18793 Plaur plasminogen activator, urokinase receptor
18797 Plcb3 phospholipase C, beta 3
18976 Pomc pro-opiomelanocortin-alpha
19013 Ppara peroxisome proliferator activated receptor alpha
19016 Pparg peroxisome proliferator activated receptor gamma
Displaying entries 1 - 10 of 151 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24217 Atp4b ATPase H+/K+ transporting subunit beta
24225 Bdnf brain-derived neurotrophic factor
24232 C3 complement C3
24267 Comt catechol-O-methyltransferase
24310 Ace angiotensin I converting enzyme
24318 Drd2 dopamine receptor D2
24367 Fgg fibrinogen gamma chain
24377 G6pd glucose-6-phosphate dehydrogenase
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31017 sdk sidekick
31234 Pdfr Pigment-dispersing factor receptor
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32556 Stim Stromal interaction molecule
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33245 ds dachsous
33627 ft fat
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30128 wnt1 wingless-type MMTV integration site family, member 1
30308 wnt10b wingless-type MMTV integration site family, member 10b
30686 myca MYC proto-oncogene, bHLH transcription factor a
30705 fgfr1a fibroblast growth factor receptor 1a
30718 notch1a notch receptor 1a
266751 adra2b adrenoceptor alpha 2B
286833 mc4r melanocortin 4 receptor
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
393141 mycb MYC proto-oncogene, bHLH transcription factor b
406207 mttp microsomal triglyceride transfer protein
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378693 npy2r.S neuropeptide Y receptor Y2 S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
394945 cfd complement factor D Xenopus tropicalis (tropical clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
397782 fgfr1.S fibroblast growth factor receptor 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
171782 abt-2 ABC transporter domain-containing protein
171994 lin-44 Abnormal cell lineage protein 44
171999 poml-2 Arylesterase
173169 eif-6 Eukaryotic translation initiation factor 6
173399 cwn-1 Protein Wnt-1
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175201 stim-1 Stromal interaction molecule 1
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850442 SRB8 Srb8p
850614 HXK1 hexokinase 1
850647 PUF3 mRNA-binding protein PUF3
851241 CNE1 calnexin
851888 DPL1 sphinganine-1-phosphate aldolase DPL1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852053 SSN2 Ssn2p
852102 IZH1 PAQR-type receptor
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0010982 Polygenic inheritance
HP:0000006 Autosomal dominant inheritance
HP:0012340 Decreased resting energy expenditure
HP:0001513 Obesity
Displaying all 2 entries
Gene ID Gene Symbol Description
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
9672 SDC3 syndecan 3

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Last updated: December 9, 2024