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MIRAGE
AKT serine/threonine kinase 3

Summary
Gene Symbol
  • AKT3
Organism
Homo sapiens (human)
NCBI Gene
10000
PubChem
10000
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Membrane
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q9Y243
  • Protein kinase Akt-3
  • Protein kinase B gamma
  • RAC-PK-gamma
  • STK-2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 17 in total
GO Term Evidence Code PMID
mitochondrial genome maintenance
positive regulation of endothelial cell proliferation
chromatin remodeling
protein phosphorylation
signal transduction
GO Hierarchy
Displaying entries 11 - 15 of 27 in total
GO Term Evidence Code PMID
ATP binding
histone H3S10 kinase activity
histone H3T11 kinase activity
histone H3T6 kinase activity
histone H2AXS139 kinase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
kinase
Functional Category
  • E: Amino acid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Displaying all 5 entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
transferase activity
Displaying all 5 entries
InterPro
AGC-kinase, C-terminal
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:10283 prostate cancer
DOID:219 colon cancer
DOID:2526 prostate adenocarcinoma
DOID:3068 glioblastoma
DOID:4450 renal cell carcinoma
Ortholog
Displaying entries 61 - 70 of 87 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
105574942 CERAT14280
105711102 AOTNA19530
105810397 PROCO14920
105986533 DIPOR10137
106835457 EQUAS26282
107585271 SINGR35107
108263416 ICTPU27156
109099970 CYPCA80241
109100905 CYPCA80241
109319932 CROPO07189
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025