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AKT serine/threonine kinase 3
Summary
- Gene Symbol
-
- AKT3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Cytoplasm
- Disease variant
- Disulfide bond
- Glycoprotein
- Membrane
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Y243 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrial genome maintenance | ||
| positive regulation of endothelial cell proliferation | ||
| chromatin remodeling | ||
| protein phosphorylation | ||
| signal transduction |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleoplasm | ||
| nucleoplasm | ||
| cytoplasm |
|
|
| Golgi apparatus | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine/threonine kinase activity | ||
| 3-phosphoinositide-dependent protein kinase activity |
GO Hierarchy
- 3-phosphoinositide-dependent protein kinase activity
- DNA-dependent protein kinase activity
- AMP-activated protein kinase activity
- eukaryotic translation initiation factor 2alpha kinase activity
- ribosomal protein S6 kinase activity
- histone H3S10 kinase activity
- histone H3T11 kinase activity
- histone H3T6 kinase activity
- histone H2AXS139 kinase activity
- histone H3S28 kinase activity
- histone H4S1 kinase activity
- histone H2AS1 kinase activity
- histone H2BS14 kinase activity
- histone H3T3 kinase activity
- histone H2AS121 kinase activity
- Rho-dependent protein serine/threonine kinase activity
- histone H2BS36 kinase activity
- histone H3S57 kinase activity
- histone H3T45 kinase activity
- histone H2AT120 kinase activity
- protein serine kinase activity
- 3-phosphoinositide-dependent protein kinase activity
- DNA-dependent protein kinase activity
- AMP-activated protein kinase activity
- eukaryotic translation initiation factor 2alpha kinase activity
- ribosomal protein S6 kinase activity
- histone H3S10 kinase activity
- histone H3T11 kinase activity
- histone H3T6 kinase activity
- histone H2AXS139 kinase activity
- histone H3S28 kinase activity
- histone H4S1 kinase activity
- histone H2AS1 kinase activity
- histone H2BS14 kinase activity
- histone H3T3 kinase activity
- histone H2AS121 kinase activity
- Rho-dependent protein serine/threonine kinase activity
- histone H2BS36 kinase activity
- histone H3S57 kinase activity
- histone H3T45 kinase activity
- histone H2AT120 kinase activity
- protein serine kinase activity
- 3-phosphoinositide-dependent protein kinase activity
- DNA-dependent protein kinase activity
- AMP-activated protein kinase activity
- eukaryotic translation initiation factor 2alpha kinase activity
- ribosomal protein S6 kinase activity
- histone H3S10 kinase activity
- histone H3T11 kinase activity
- histone H3T6 kinase activity
- histone H2AXS139 kinase activity
- histone H3S28 kinase activity
- histone H4S1 kinase activity
- histone H2AS1 kinase activity
- histone H2BS14 kinase activity
- histone H3T3 kinase activity
- histone H2AS121 kinase activity
- Rho-dependent protein serine/threonine kinase activity
- histone H2BS36 kinase activity
- histone H3S57 kinase activity
- histone H3T45 kinase activity
- histone H2AT120 kinase activity
- protein serine kinase activity
molecular function
catalytic activity [inference]
transferase activity [inference]
transferase activity, transferring phosphorus-containing groups [inference]
kinase activity [inference]
protein kinase activity
protein serine/threonine kinase activity
histone kinase activity [inference]
phosphotransferase activity, alcohol group as acceptor [inference]
protein kinase activity
protein serine/threonine kinase activity
histone kinase activity [inference]
catalytic activity, acting on a protein [inference]
protein kinase activity
protein serine/threonine kinase activity
histone kinase activity [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- kinase
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| kinase activity |
| nucleotide binding |
| phosphorylation |
| transferase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer | |
| DOID:219 | colon cancer | |
| DOID:2526 | prostate adenocarcinoma | |
| DOID:3068 | glioblastoma | |
| DOID:4450 | renal cell carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100480414 | AILME13861 | ||
| 100513811 | PIGXX00175 | ||
| 100553927 | ANOCA15953 | ||
| 100604331 | NOMLE30603 | ||
| 100609583 | PANTR24055 | ||
| 100657536 | LOXAF13811 | ||
| 100691860 | ORENI13409 | ||
| 100724315 | CAVPO07992 | ||
| 100752454 | CRIGR17586 | ||
| 100955276 | OTOGA04429 |
