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MIRAGE
AKT serine/threonine kinase 3

Summary
Gene Symbol
  • AKT3
Organism
Homo sapiens (human)
NCBI Gene
10000
PubChem
10000
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Membrane
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q9Y243
  • Protein kinase Akt-3
  • Protein kinase B gamma
  • RAC-PK-gamma
  • STK-2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 17 in total
GO Term Evidence Code PMID
mitochondrial genome maintenance
positive regulation of endothelial cell proliferation
chromatin remodeling
protein phosphorylation
signal transduction
GO Hierarchy
Displaying entries 1 - 5 of 27 in total
GO Term Evidence Code PMID
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine kinase activity
protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
kinase
Functional Category
  • E: Amino acid transport and metabolism
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Displaying all 5 entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
transferase activity
Displaying all 5 entries
InterPro
AGC-kinase, C-terminal
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:10283 prostate cancer
DOID:219 colon cancer
DOID:2526 prostate adenocarcinoma
DOID:3068 glioblastoma
DOID:4450 renal cell carcinoma
Ortholog
Displaying entries 41 - 50 of 87 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
101804556 ANAPP00843
101819472 FICAL03361
101869818 MELUD11250
101946510 CHRPI13621
102027606 CHILA01368
102144461 MACFA19442
102174051 CAPHI06673
102346546 LATCH12131
102439923 MYOLU14431
102448379 PELSI12990
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025