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cardiolipin synthase 1

Summary

Gene Symbol

CRLS1

Organism

Bos indicus (zebu cattle)

External Links

NCBI Gene: 109568132
KEGG Gene ID: biu:109568132
PubChem: 109568132

Annotation

Keyword

Phospholipid biosynthesis
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6P5CSE1
A0A6P5CTC8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cardiolipin biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

cardiolipin metabolic process [inference]

cardiolipin biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylglycerol biosynthetic process [inference]

cardiolipin biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cardiolipin synthase activity	IEA	30032202
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

CDP-alcohol phosphatidyltransferase activity [inference]

CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity

phosphatidyltransferase activity [inference]

cardiolipin synthase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K08744

Name

cardiolipin synthase (CMP-forming) [EC:2.7.8.41]

References

Rhea

RHEA:32931

a CDP-1,2-diacyl-sn-glycerol + 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)

H⁺ + CMP + a cardiolipin

Enzyme

2.7.8.41

PMID

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Last updated: August 19, 2024

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Acknowledgements