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glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Summary

Gene Symbol

GNE

Organism

Aythya fuligula (tufted duck)

External Links

NCBI Gene: 116501011
KEGG Gene ID: aful:116501011
PubChem: 116501011

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
UDP-N-acetylglucosamine metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

phosphorus metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

organic substance metabolic process [inference]

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

phosphorus metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylglucosamine metabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	22301074
N-acylmannosamine kinase activity	IEA	30032202
UDP-N-acetylglucosamine 2-epimerase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

N-acylmannosamine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

N-acylmannosamine kinase activity

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds

isomerase activity [inference]

racemase and epimerase activity [inference]

racemase and epimerase activity, acting on carbohydrates and derivatives [inference]

UDP-N-acetylglucosamine 2-epimerase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Galloanserae

Group Name

Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 4** entries
Gene Ontology
N-acylmannosamine kinase activity
UDP-N-acetylglucosamine 2-epimerase activity
UDP-N-acetylglucosamine metabolic process
hexokinase activity

Displaying **all 4** entries
InterPro
ATPase, nucleotide binding domain
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase
ROK family
UDP-N-acetylglucosamine 2-epimerase domain

KEGG BRITE Database

Orthology

K12409

Name

bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:3.2.1.183 2.7.1.60]

References

Ortholog

Displaying entries **1 - 10** of 15 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Gallus gallus	427285	9031_0:0042f1
Meleagris gallopavo	100541275	9103_1:003ef8
Anas platyrhynchos	101793177	8839_0:003b8b
Anser cygnoides	106046482	8845_0:003384
Coturnix japonica	107306391	93934_0:003a35
Numida meleagris	110389421	8996_0:003958
Phasianus colchicus	116240072	9054_0:003305
Oxyura jamaicensis	118156266	8884_0:0039d4
Cygnus atratus	118256855	8868_0:0037f8
Cygnus olor	121061352	8869_0:003b70

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024