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proprotein convertase subtilisin/kexin type 2
Summary
- Gene Symbol
-
- Pcsk2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zymogen
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| insulin processing | ||
| proteolysis | ||
| protein autoprocessing | ||
| peptide hormone processing | ||
| nervous system development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule lumen | ||
| membrane | ||
| secretory granule | ||
| perikaryon | ||
| neuronal cell body |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- neuroendocrine convertase 2
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| hydrolase activity |
| peptide hormone processing |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Peptidase S8/S53 domain |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 117704080 | 61156_0:000ecb | |||
| 118581687 | 38674_0:0015c5 | |||
| 118881888 | BALMU20831 | |||
| 119815398 | 1047088_0:001e7b | |||
| 121460161 | 111838_0:003046 | |||
| 122096086 | 105255_0:0042ba | |||
| 122215838 | PANLE01614 | |||
| 124088855 | 9995_0:0007a3 | |||
| 124970768 | 30640_0:0009d4 | |||
| 125352316 | 214514_0:001bdb |
