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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
AKT serine/threonine kinase 2
Summary
- Gene Symbol
-
- AKT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Diabetes mellitus
- Disease variant
- Disulfide bond
- Endosome
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Manganese
- Metal-binding
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to insulin stimulus | ||
| regulation of cell migration | ||
| insulin receptor signaling pathway | ||
| peripheral nervous system myelin maintenance | ||
| positive regulation of glycogen biosynthetic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| early endosome | ||
| cell cortex | ||
| nucleoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein serine/threonine kinase activity | ||
| protein serine kinase activity | ||
| metal ion binding | ||
| molecular function activator activity | ||
| ATP binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0112263 | hypoinsulinemic hypoglycemia with hemihypertrophy | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10763 | hypertension | |
| DOID:11612 | polycystic ovary syndrome | |
| DOID:1380 | endometrial cancer | |
| DOID:14330 | Parkinson's disease | |
| DOID:1574 | alcohol use disorder | |
| DOID:162 | cancer | |
| DOID:2526 | prostate adenocarcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101581803 | OCTDE26587 | ||
| 103661038 | URSMA29683 | ||
| 114038294 | VOMUR25339 | ||
| 100959825 | OTOGA01567 | ||
| 102017721 | CHILA24698 | ||
| 105723415 | AOTNA35376 | ||
| 101040766 | SAIBB37699 | ||
| 101614937 | JACJA22457 | ||
| 118299293 | SCOMX22881 | ||
| 117035083 | RHIFE00846 |
