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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

5'-3' exoribonuclease 2

Summary

Gene Symbol

XRN2

Organism

Homo sapiens (human)

External Links

NCBI Gene

22803

PubChem

22803

Alliance of Genome Resources

HGNC:12836

Annotation

Keyword

Acetylation
Alternative splicing
DNA-binding
Exonuclease
Methylation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Transcription termination
Zinc-finger
mRNA processing

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9H0D6	DHM1-like protein
B4DZC3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
RNA catabolic process	TAS	10409438
spermatogenesis	IEP	10409438
RNA metabolic process	ISS
hippocampus development	IEA
neuron differentiation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

anatomical structure development [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
nucleolus	IDA	12429849
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
3'-5'-RNA exonuclease activity	EXP	23482395
transcription termination site sequence-specific DNA binding	IDA	21700224
RNA binding	IBA
RNA binding	HDA	22658674 22681889
nuclease activity	TAS	10409438

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity

exonuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5' exonuclease activity [inference]

3'-5'-RNA exonuclease activity

5'-3' exonuclease activity

5'-3' RNA exonuclease activity

exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

binding [inference]

protein binding

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

5'-3' exoribonuclease A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
5'-3' RNA exonuclease activity
hydrolase activity
nuclease activity

Displaying **all 3** entries
InterPro
5'-3' exoribonuclease
Xrn1, N-terminal
Xrn1, helical domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080202	adenoid cystic carcinoma	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources

Ortholog

Displaying entries **81 - 82** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Panthera leo	122215872		PANLE01305
Ursus americanus	123779045		URSAM07854

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025