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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
folate receptor alpha
Summary
- Gene Symbol
-
- FOLR1
- Aliases
-
- FRĪ±
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endosome
- Folate-binding
- GPI-anchor
- Neurodegeneration
- Receptor
- Reference proteome
- Secreted
- Signal
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P15328 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to folic acid | ||
| anterior neural tube closure | ||
| cardiac neural crest cell migration involved in outflow tract morphogenesis | ||
| axon regeneration | ||
| cell adhesion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| basolateral plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| folic acid receptor activity | ||
| folic acid binding | ||
| signaling receptor activity | ||
| protein binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4588 | secretory meningioma | |
| DOID:4594 | microcystic meningioma | |
| DOID:4647 | trilateral retinoblastoma | |
| DOID:4648 | familial retinoblastoma | |
| DOID:4766 | embryoma | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:5517 | stomach carcinoma | |
| DOID:5672 | large intestine cancer | |
| DOID:574 | peripheral nervous system disease | |
| DOID:5750 | endometrial serous adenocarcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001249 | Intellectual disability |
| HP:0001250 | Seizure |
| HP:0002180 | Neurodegeneration |
| HP:0002376 | Developmental regression |
| Disease ID | Disease Name |
|---|---|
| OMIM:613068 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100183675 | CIOIN08081 | ||
| 100073336 | ZFIN:ZDB-GENE-070615-23 | DANRE09829 | |
| 103026309 | ASTMX04343 | ||
| 108277654 | ICTPU09855 | ||
| 113581593 | ELEEL26344 | ||
| 115206595 | SALTR111138 | ||
| 115561632 | GADMO18926 | ||
| 101171932 | ORYLA03593 | ||
| 115569735 | SPAAU17263 | ||
| 444543 | Xenbase:XB-GENE-6254887 |
