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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
folate receptor alpha
Summary
- Gene Symbol
-
- FOLR1
- Aliases
-
- FRĪ±
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endosome
- Folate-binding
- GPI-anchor
- Neurodegeneration
- Receptor
- Reference proteome
- Secreted
- Signal
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P15328 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of canonical Wnt signaling pathway | ||
| neural crest cell migration involved in heart formation | ||
| sperm-egg recognition | ||
| heart looping | ||
| fusion of sperm to egg plasma membrane involved in single fertilization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| ER to Golgi transport vesicle membrane |
|
|
| endoplasmic reticulum-Golgi intermediate compartment membrane |
|
|
| endosome | ||
| transport vesicle |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| folic acid receptor activity | ||
| folic acid binding | ||
| signaling receptor activity | ||
| protein binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4588 | secretory meningioma | |
| DOID:4594 | microcystic meningioma | |
| DOID:4647 | trilateral retinoblastoma | |
| DOID:4648 | familial retinoblastoma | |
| DOID:4766 | embryoma | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:5517 | stomach carcinoma | |
| DOID:5672 | large intestine cancer | |
| DOID:574 | peripheral nervous system disease | |
| DOID:5750 | endometrial serous adenocarcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001249 | Intellectual disability |
| HP:0001250 | Seizure |
| HP:0002180 | Neurodegeneration |
| HP:0002376 | Developmental regression |
| Disease ID | Disease Name |
|---|---|
| OMIM:613068 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100689330 | CRIGR25255 | ||
| 14275 | MGI:95568 | MOUSE56360 | |
| 171049 | RGD:71032 | RATNO19865 | |
| 101571684 | OCTDE20160 | ||
| 100015543 | MONDO24248 | ||
| 100015612 | MONDO24248 | ||
| 100015645 | MONDO24248 | ||
| 103678021 | URSMA22163 | ||
| 113905541 | BOBOX34867 | ||
| 100944015 | OTOGA19033 |
