GlyCosmos Portal

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
vacuolar proton-transporting V-type ATPase, V0 domain	IEA
proton-transporting V-type ATPase complex		33065002
transmembrane transporter complex	IEA
plasma membrane	IBA IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

vacuolar proton-transporting V-type ATPase complex

proton-transporting two-sector ATPase complex, proton-transporting domain [inference]

proton-transporting V-type ATPase, V0 domain [inference]

vacuolar proton-transporting V-type ATPase, V0 domain

transmembrane transporter complex

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

vacuolar proton-transporting V-type ATPase complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATPase binding	IBA
proton-transporting ATPase activity, rotational mechanism	IEA
protein binding	IPI	16415858

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

binding [inference]

protein binding

enzyme binding [inference]

ATPase binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000185344

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K02154

Name

V-type H+-transporting ATPase subunit a

References

Disease

Disease Ontology

Displaying entries **61 - 70** of **121** in total

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DO ID	Disease Name	Source
DOID:10941	intracranial aneurysm	DisGeNET
DOID:11383	cryptorchidism	DisGeNET
DOID:11712	lipoatrophic diabetes mellitus	DisGeNET
DOID:11830	myopia	DisGeNET
DOID:11832	visual epilepsy	DisGeNET
DOID:11836	clubfoot	DisGeNET DisGeNET
DOID:12053	cryptococcosis	DisGeNET
DOID:1222	cartilage disease	DisGeNET
DOID:12336	male infertility	DisGeNET
DOID:12347	osteogenesis imperfecta	DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of **114** in total

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000023	Inguinal hernia
HP:0000028	Cryptorchidism
HP:0000160	Narrow mouth
HP:0000218	High palate
HP:0000252	Microcephaly
HP:0000253	Progressive microcephaly
HP:0000260	Wide anterior fontanel
HP:0000270	Delayed cranial suture closure
HP:0000272	Malar flattening

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:219200	autosomal recessive cutis laxa type 2A
ORPHA:357074	autosomal recessive cutis laxa type 2, classic type
OMIM:278250	wrinkly skin syndrome
ORPHA:2834	wrinkly skin syndrome

PubChem Disease

GHR Health Conditions

Cutis laxa

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Cutis laxa

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **41 - 50** of **106** in total

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Species	Gene ID	Orthologous MAtrix
Papio anubis	101014564	PAPAN40056
Mandrillus leucophaeus	105545849	MANLE07904
Gorilla gorilla gorilla	101141834	GORGO04843
Pan paniscus	100974286	PANPA10675
Pan troglodytes	452354	PANTR07217
Pongo abelii	100939293	PONAB06556
Canis lupus familiaris	486245	CANLF10244
Vulpes vulpes	112933819	VULVU29871
Ursus americanus	123780006	URSAM01651
Ailuropoda melanoleuca	105238191	AILME18997

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements