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Standards Ontologies Notations
Guidelines
MIRAGE
angiotensin I converting enzyme

Summary
Gene Symbol
  • Ace
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
24310
PubChem
24310
Alliance of Genome Resources
Annotation
Keyword
  • Alternative promoter usage
  • Calmodulin-binding
  • Carboxypeptidase
  • Cell membrane
  • Cytoplasm
  • Disulfide bond
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Transmembrane helix
  • Zinc
Proteins
Displaying 1 entry
UniProt Protein Name
P47820
  • Dipeptidyl carboxypeptidase I
  • Kininase II
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 91 in total
GO Term Evidence Code PMID
response to hypoxia
kidney development
kidney development
kidney development
kidney development
GO Hierarchy
Displaying entries 1 - 5 of 39 in total
GO Term Evidence Code PMID
actin binding
endopeptidase activity
carboxypeptidase activity
metallocarboxypeptidase activity
metallocarboxypeptidase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
angiotensin-converting enzyme
Functional Category
  • E: Amino acid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 6 entries
Gene Ontology
carboxypeptidase activity
hydrolase activity
metal ion binding
metallopeptidase activity
peptidyl-dipeptidase activity
proteolysis
Displaying 1 entry
InterPro
Peptidase M2, peptidyl-dipeptidase A
Alliance of Genome Resources
Expression
Displaying all 5 entries
Location References
Disease
Disease Ontology
Displaying entries 1 - 10 of 27 in total
DO ID Disease Name Source
DOID:0050851 glomerulosclerosis
DOID:0050855 renal fibrosis
DOID:0060071 pre-malignant neoplasm
DOID:0110861 autosomal recessive polycystic kidney disease
DOID:0111128 focal segmental glomerulosclerosis 1
DOID:10652 Alzheimer's disease
DOID:10763 hypertension
DOID:11476 osteoporosis
DOID:1184 nephrotic syndrome
DOID:12986 leukostasis
Ortholog
Displaying entries 41 - 50 of 55 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
109060366 CYPCA113140
109099167 CYPCA105584
109318963 CROPO06668
113489137 ATHCN20156
113584762 ELEEL34648
114581443 PODMU00436
114815136 ORNAN03168
115059877 ECHNA46481
115159185 SALTR00316
115200950 SALTR100933
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025