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Guidelines

MIRAGE

interleukin 2 receptor subunit alpha

Summary

Gene Symbol

Il2ra

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25704

PubChem

25704

Alliance of Genome Resources

RGD:2895

Annotation

Keyword

Disulfide bond
Glycoprotein
Immunity
Receptor
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P26897
A6JLS0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 17** of 17 in total

« First

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GO Term	Evidence Code	PMID
activated T cell proliferation	ISO
regulation of CD4-positive, alpha-beta T cell proliferation	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

T cell homeostasis

immune response [inference]

inflammatory response to antigenic stimulus

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

T cell proliferation [inference]

activated T cell proliferation

lymphocyte proliferation

T cell proliferation [inference]

activated T cell proliferation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

T cell proliferation [inference]

activated T cell proliferation

lymphocyte proliferation

T cell proliferation [inference]

activated T cell proliferation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-2-mediated signaling pathway

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

leukocyte apoptotic process [inference]

lymphocyte apoptotic process [inference]

T cell apoptotic process [inference]

activation-induced cell death of T cells

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation

T cell proliferation [inference]

activated T cell proliferation

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

T cell proliferation [inference]

activated T cell proliferation

lymphocyte proliferation

T cell proliferation [inference]

activated T cell proliferation

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

T cell homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

leukocyte homeostasis [inference]

lymphocyte homeostasis [inference]

T cell homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

inflammatory response to antigenic stimulus

immune response [inference]

inflammatory response to antigenic stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of tolerance induction [inference]

regulation of T cell tolerance induction

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

regulation of alpha-beta T cell activation [inference]

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell activation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-2-mediated signaling pathway

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

regulation of alpha-beta T cell activation [inference]

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell activation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

negative regulation of T cell proliferation

regulation of activated T cell proliferation [inference]

positive regulation of activated T cell proliferation

regulation of T cell homeostatic proliferation

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

regulation of alpha-beta T cell activation [inference]

regulation of alpha-beta T cell proliferation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell activation [inference]

regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of activated T cell proliferation

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation

negative regulation of T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

positive regulation of T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	ISO
cell surface	IDA	10210776

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
interleukin-2 receptor activity	ISO
interleukin-2 receptor activity	IPI	2592769
interleukin-2 binding	ISO
interleukin-2 binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

growth factor binding [inference]

interleukin-2 binding

cytokine binding [inference]

interleukin-2 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

interleukin-2 receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

interleukin-2 receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Interleukin-2 receptor subunit alpha

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
inflammatory response
interleukin-2 binding
interleukin-2 receptor activity
interleukin-2-mediated signaling pathway

Displaying **all 3** entries
InterPro
Interleukin-2 receptor alpha
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cell surface	PMID:10210776

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050200	Korean hemorrhagic fever	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources
DOID:9351	diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 39 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3559	HGNC:6008	HUMAN00163
Mus musculus	16184	HGNC:6008	MOUSE32263
Homo sapiens	25704	HGNC:6008
Bos taurus	281861		BOVIN04315
Sus scrofa	396814		PIGXX00831
Canis lupus familiaris	403870		CANLF06582
Ovis aries	443435		SHEEP04117
Pan troglodytes	450884		PANTR00083
Felis catus	493953		FELCA15753
Macaca mulatta	574300		MACMU45201

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Last updated: August 4, 2025