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MIRAGE
GATA binding protein 2
Summary
- Gene Symbol
-
- GATA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- DNA-binding
- Disease variant
- Isopeptide bond
- Methylation
- Nucleus
- Phagocytosis
- Phosphoprotein
- Reference proteome
- Repeat
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| P23769 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of forebrain neuron differentiation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
negative regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of vesicle-mediated transport [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleus | ||
| nucleoplasm | ||
| nucleoplasm | ||
| transcription regulator complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA-binding transcription factor activity, RNA polymerase II-specific | ||
| DNA-binding transcription factor activity, RNA polymerase II-specific | ||
| transcription coregulator binding | ||
| transcription coactivator binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Transcription factor
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| sequence-specific DNA binding |
| zinc ion binding |
| InterPro |
|---|
| Zinc finger, GATA-type |
| Zinc finger, NHR/GATA-type |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:0111947 | immunodeficiency 21 | |
| DOID:1596 | depressive disorder | |
| DOID:8692 | myeloid leukemia | |
| DOID:9119 | acute myeloid leukemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2624 | Xenbase:XB-GENE-478165 | ||
| 2625 | SGD:S000003646 | ||
| 2626 | SGD:S000003646 | ||
| 14461 | MOUSE47715 | ||
| 14463 | SGD:S000001873 | ||
| 25159 | RATNO31928 | ||
| 396912 | PIGXX04697 | ||
| 460672 | PANTR32117 | ||
| 705551 | MACMU28337 | ||
| 100017255 | MONDO29820 |
