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MIRAGE
huntingtin interacting protein 1

Summary
Gene Symbol
  • HIP1
Organism
Homo sapiens (human)
NCBI Gene
3092
PubChem
3092
Alliance of Genome Resources
JoGo
HIP1
TogoVar
HIP1
Annotation
Keyword
  • 3D-structure
  • Actin-binding
  • Activator
  • Alternative splicing
  • Apoptosis
  • Chromosomal rearrangement
  • Coiled coil
  • Cytoplasm
  • Cytoplasmic vesicle
  • Differentiation
  • Endocytosis
  • Membrane
  • Neurodegeneration
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Transcription regulation
Proteins
Displaying all 2 entries
UniProt Protein Name
B4DK46
O00291
  • Huntingtin-interacting protein I
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 21 in total
GO Term Evidence Code PMID
endocytosis
apoptotic process
actin filament organization
regulation of endocytosis
cell differentiation
GO Hierarchy
Displaying entries 1 - 5 of 18 in total
GO Term Evidence Code PMID
nucleus
cytoplasm
Golgi apparatus
cytosol
cytoskeleton
GO Hierarchy
Displaying entries 6 - 10 of 21 in total
GO Term Evidence Code PMID
clathrin light chain binding
clathrin light chain binding
phosphatidylinositol-3-phosphate binding
phosphatidylinositol binding
glutamate receptor binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
huntingtin interacting protein
Functional Category
  • E: Amino acid transport and metabolism
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying all 10 entries
Gene Ontology
actin binding
actin filament binding
actin filament organization
clathrin adaptor activity
clathrin binding
clathrin coat assembly
clathrin light chain binding
phosphatidylinositol-3,4-bisphosphate binding
phosphatidylinositol-3,5-bisphosphate binding
phospholipid binding
Displaying all 7 entries
InterPro
AP180 N-terminal homology (ANTH) domain
ENTH domain
ENTH/VHS
Huntingtin-interacting protein 1, clathrin-binding domain
I/LWEQ domain superfamily
I/LWEQ domain
Sla2 family
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026