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small nuclear ribonucleoprotein 200 (U5)

Summary

Gene Symbol

Snrnp200

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

320632

PubChem

320632

Alliance of Genome Resources

MGI:2444401

Annotation

Keyword

Acetylation
Coiled coil
Helicase
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Repeat
Ribonucleoprotein
Spliceosome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6P4T2	BRR2 homolog U5 snRNP-specific 200 kDa protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	ISO
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	IBA
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	IEA
mRNA splicing, via spliceosome	ISS
mRNA splicing, via spliceosome	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

Displaying entries **11 - 15** of 18 in total

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GO Term	Evidence Code	PMID
U4/U6 x U5 tri-snRNP complex	ISO
U4/U6 x U5 tri-snRNP complex	IEA
U2-type precatalytic spliceosome	ISS
U2-type precatalytic spliceosome	ISO
U2-type catalytic step 1 spliceosome	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

Sm-like protein family complex [inference]

small nuclear ribonucleoprotein complex [inference]

spliceosomal snRNP complex [inference]

U5 snRNP

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

nuclear protein-containing complex [inference]

spliceosomal complex

U2-type spliceosomal complex [inference]

precatalytic spliceosome [inference]

U2-type precatalytic spliceosome

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome

small nuclear ribonucleoprotein complex [inference]

spliceosomal snRNP complex [inference]

U5 snRNP

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

catalytic complex [inference]

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome

ribonucleoprotein complex [inference]

spliceosomal complex

U2-type spliceosomal complex [inference]

precatalytic spliceosome [inference]

U2-type precatalytic spliceosome

catalytic step 1 spliceosome [inference]

U2-type catalytic step 1 spliceosome

catalytic step 2 spliceosome

small nuclear ribonucleoprotein complex [inference]

spliceosomal snRNP complex [inference]

U5 snRNP

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleic acid binding	IEA
RNA helicase activity	ISS
RNA helicase activity	ISO
RNA helicase activity	IBA
helicase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity

RNA helicase activity

catalytic activity, acting on RNA [inference]

RNA helicase activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity

RNA helicase activity

ATP-dependent activity, acting on RNA [inference]

RNA helicase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

helicase

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
hydrolase activity
nucleotide binding

Displaying **all 9** entries
InterPro
C2 domain superfamily
DEAD/DEAH box helicase domain
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
Immunoglobulin E-set
P-loop containing nucleoside triphosphate hydrolase
Sec63 domain
Winged helix DNA-binding domain superfamily
Winged helix-like DNA-binding domain superfamily

Ortholog

Displaying entries **1 - 10** of 87 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	6487	Xenbase:XB-GENE-941048
Xenopus tropicalis	20441	Xenbase:XB-GENE-941048
Homo sapiens	23020	Xenbase:XB-GENE-941048	HUMAN63849
Xenopus tropicalis	64445	Xenbase:XB-GENE-941048
Rattus norvegicus	296126		RATNO27043
Xenopus tropicalis	320632	Xenbase:XB-GENE-981975
Xenopus tropicalis	393326	Xenbase:XB-GENE-941048
Xenopus tropicalis	402789	Xenbase:XB-GENE-941048
Xenopus tropicalis	407659	Xenbase:XB-GENE-941048
Pan troglodytes	459413		PANTR28221