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Cdc50 Cell division cycle 50 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32615, updated on 9-Dec-2024

Summary

Official Symbol
Cdc50provided by FlyBase
Official Full Name
Cell division cycle 50provided by FlyBase
Primary source
FLYBASE:FBgn0030752
Locus tag
Dmel_CG9947
See related
AllianceGenome:FB:FBgn0030752
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CDC50; CG9947; Dmel\CG9947
Summary
Predicted to enable structural molecule activity. Predicted to be involved in phospholipid translocation. Predicted to be located in membrane. Predicted to be part of phospholipid-translocating ATPase complex. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is expressed in adult head; embryonic/larval midgut; and organism. Orthologous to several human genes including TMEM30A (transmembrane protein 30A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Cdc50 in Genome Data Viewer
Location:
14C4-14C6; 1-53 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16438680..16441296, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16331454..16335329, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene TNF-receptor-associated factor-like Neighboring gene Annexin B11 Neighboring gene hangover Neighboring gene rings lost Neighboring gene eukaryotic translation initiation factor 2 subunit alpha Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural molecule activity  
Process Evidence Code Pubs
involved_in phospholipid translocation  
Component Evidence Code Pubs
is_active_in Golgi apparatus  
is_active_in endoplasmic reticulum  
located_in membrane  
part_of phospholipid-translocating ATPase complex  
is_active_in plasma membrane  

General protein information

Preferred Names
cell division cycle 50
Names
CG9947-PA
CG9947-PB
Cdc50-PA
Cdc50-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    16438680..16441296 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298398.2 → NP_001285327.1  cell division cycle 50, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285327.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8STD2, X2JKP3
    Conserved Domains (1) summary
    pfam03381
    Location:67 → 340
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
  2. NM_132900.3 → NP_573128.2  cell division cycle 50, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573128.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8STD2, Q9VXG0
    Related
    FBpp0074076
    Conserved Domains (1) summary
    pfam03381
    Location:67 → 340
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
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