GlyCosmos Portal

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GO Term	Evidence Code	PMID
acetyl-CoA carboxylase activity	IBA IDA	19236960 20457939 20952656 26976583
metal ion binding	IEA
ATP binding	IEA
protein binding	IPI	16794074 20085763 20457939 20952656
biotin binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-carbon bonds [inference]

CoA carboxylase activity [inference]

acetyl-CoA carboxylase activity

binding [inference]

protein binding

identical protein binding

amide binding [inference]

biotin binding

small molecule binding [inference]

vitamin binding [inference]

biotin binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

biotin binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

biotin binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

biotin binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

biotin binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

sulfur compound binding [inference]

biotin binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000076555

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K01946

Name

acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]

References

Rhea

RHEA:11308

hydrogencarbonate + ATP + acetyl-CoA

H⁺ + phosphate + ADP + malonyl-CoA

Enzyme

6.4.1.2

PMID

Disease

Disease Ontology

Displaying entries **41 - 48** of 48 in total

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DO ID	Disease Name	Source
DOID:8850	salivary gland cancer	DisGeNET
DOID:9256	colorectal cancer	DisGeNET
DOID:934	viral infectious disease	DisGeNET
DOID:9351	diabetes mellitus	DisGeNET DisGeNET
DOID:9352	type 2 diabetes mellitus	DisGeNET DisGeNET
DOID:9408	acute myocardial infarction	DisGeNET
DOID:9452	steatotic liver disease	DisGeNET DisGeNET DisGeNET Alliance of Genome Resources
DOID:9970	obesity	DisGeNET Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006663
Gene Name: acetyl-CoA carboxylase beta

Ortholog

Displaying entries **71 - 80** of 90 in total

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Species	Gene ID	Orthologous MAtrix
Ficedula albicollis	101819106	FICAL01889
Chlorocebus sabaeus	103239081	CHLSB02616
Rhinopithecus bieti	108534384	RHIBE19295
Rhinopithecus roxellana	104660172	RHIRO25511
Nomascus leucogenys	100606756	NOMLE00602
Anabas testudineus	113150319	ANATE12119
Podarcis muralis	114581463	PODMU00791
Sinocyclocheilus grahami	107597297	SINGR19673
Amphiprion ocellaris	111568287	AMPOC04240
Equus asinus asinus	106848074	EQUAS30195

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements