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Galactose-1-phosphate uridylyltransferase

Summary

Gene Symbol

Galt

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33935

PubChem

33935

Alliance of Genome Resources

FB:FBgn0263200

Annotation

Keyword

Galactose metabolism
Metal-binding
Nucleotidyltransferase
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
M9PB52
Q9VMA2	UDP-glucose--hexose-1-phosphate uridylyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
UDP-D-galactose metabolic process	IMP	20519569
galactose catabolic process via UDP-galactose	IBA IMP	20519569 27562100
UDP-glucose metabolic process	IMP	20519569
galactose metabolic process	IEA IMP	22736462
UDP-galactose biosynthetic process	IMP	27562100

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

phosphorus metabolic process [inference]

UDP-glucose metabolic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

galactose metabolic process

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

carbohydrate derivative metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

galactose catabolic process [inference]

galactose catabolic process via UDP-galactose

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

phosphorus metabolic process [inference]

UDP-glucose metabolic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-glucose metabolic process

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

UDP-D-galactose metabolic process

UDP-galactose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

UDP-galactose biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	ISS
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA
UDP-glucose:hexose-1-phosphate uridylyltransferase activity	IBA IEA IMP	20519569 27562100

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

uridylyltransferase activity [inference]

UDP-glucose:hexose-1-phosphate uridylyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Galactose-1-phosphate

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
UDP-glucose
galactose catabolic process via UDP-galactose
galactose metabolic process
metal ion binding
nucleotidyltransferase activity
transferase activity
zinc ion binding

Displaying **all 5** entries
InterPro
Galactose-1-phosphate uridyl transferase, C-terminal
Galactose-1-phosphate uridyl transferase, N-terminal
Galactose-1-phosphate uridyl transferase, class I His-active site
Galactose-1-phosphate uridyl transferase, class I
HIT-like superfamily

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0111459	classic galactosemia	Alliance of Genome Resources
DOID:9870	galactosemia	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 44 in total

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Species	Gene ID	OrthoDB
Drosophila erecta	6543041	7220_1:00180e
Drosophila grimshawi	6566948	7222_1:000e56
Drosophila mojavensis	6577137	7230_0:001551
Drosophila persimilis	6593424	7234_1:00197b
Drosophila sechellia	6611421	7238_1:00056b
Drosophila virilis	6627450	7244_1:002730
Drosophila willistoni	6643619	7260_0:0014ca
Drosophila simulans	6731248	7240_1:00039f
Drosophila suzukii	108017367	28584_0:000374
Drosophila biarmipes	108033713	125945_1:000fa1

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Acknowledgements