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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leukotriene C4 synthase
Summary
- Gene Symbol
-
- LTC4S
- Aliases
-
- MGC33147
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Endoplasmic reticulum
- Leukotriene biosynthesis
- Lipid biosynthesis
- Lyase
- Nucleus
- Phosphoprotein
- Reference proteome
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16873 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| leukotriene biosynthetic process | ||
| leukotriene metabolic process | ||
| long-chain fatty acid biosynthetic process | ||
| cellular oxidant detoxification |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear envelope | ||
| intracellular membrane-bounded organelle |
|
|
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| nuclear outer membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lipid binding | ||
| glutathione peroxidase activity | ||
| leukotriene-C4 synthase activity | ||
| enzyme activator activity | ||
| protein binding |
GO Hierarchy
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110045 | Alzheimer's disease 12 | |
| DOID:0110046 | Alzheimer's disease 13 | |
| DOID:0110047 | Alzheimer's disease 14 | |
| DOID:0110048 | Alzheimer's disease 15 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10907 | microcephaly | |
| DOID:10952 | nephritis | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:114 | heart disease | |
| DOID:11847 | coronary thrombosis |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000252 | Microcephaly |
| HP:0001252 | Hypotonia |
| HP:0001263 | Global developmental delay |
| HP:0001522 | Death in infancy |
| HP:0001531 | Failure to thrive in infancy |
| Disease ID | Disease Name |
|---|---|
| OMIM:614037 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002479
- Gene Name
- leukotriene C4 synthase
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 113032002 | ASTCA25838 | ||
| 115568447 | SPAAU63318 | ||
| 495166 | Xenbase:XB-GENE-981582 | ||
| 100127769 | Xenbase:XB-GENE-981579 | ||
| 103817479 | SERCA12372 | ||
| 105590406 | CERAT38512 | ||
| 705233 | MACMU39557 | ||
| 105483999 | MACNE39832 | ||
| 105537281 | MANLE24420 | ||
| 607316 | CANLF01974 |
