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CD46 molecule

Summary

Gene Symbol

CD46

Organism

Homo sapiens (human)

External Links

NCBI Gene

4179

PubChem

4179

Alliance of Genome Resources

HGNC:6953

Annotation

Keyword

3D-structure
Alternative splicing
Complement pathway
Cytoplasmic vesicle
Direct protein sequencing
Disease variant
Disulfide bond
Fertilization
Glycoprotein
Hemolytic uremic syndrome
Host cell receptor for virus entry
Host-virus interaction
Phosphoprotein
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P15529	TLX Trophoblast leukocyte common antigen

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
adaptive immune response	IC	12540904
T cell mediated immunity	IMP	23086448
T cell mediated immunity	IBA
complement activation, classical pathway	IEA
single fertilization	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

T cell mediated immunity

complement activation [inference]

complement activation, classical pathway

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

immune response [inference]

adaptive immune response

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

humoral immune response [inference]

complement activation [inference]

complement activation, classical pathway

innate immune response

reproductive process [inference]

fertilization [inference]

single fertilization

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

adaptive immune response

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

humoral immune response [inference]

complement activation [inference]

complement activation, classical pathway

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of immune effector process [inference]

positive regulation of memory T cell differentiation

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

positive regulation of memory T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune effector process [inference]

positive regulation of memory T cell differentiation

regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of lymphocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response [inference]

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

positive regulation of memory T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

extracellular regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of immune effector process [inference]

positive regulation of memory T cell differentiation

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

positive regulation of memory T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

positive regulation of memory T cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

extracellular regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

positive regulation of memory T cell differentiation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response [inference]

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation [inference]

complement activation, classical pathway

positive regulation of memory T cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

extracellular regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
inner acrosomal membrane	IEA
extracellular space	IBA
plasma membrane	TAS
plasma membrane	IDA	20534589
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

inner acrosomal membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
virus receptor activity	IEA
protein binding	IPI	18796626 23086448 32296183
signaling receptor activity	TAS	8402913
cadherin binding	IPI	23086448

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

exogenous protein binding [inference]

virus receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

membrane cofactor protein

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0080176	meningococcal meningitis	Alliance of Genome Resources
DOID:0080301	atypical hemolytic-uremic syndrome	Alliance of Genome Resources
DOID:10591	pre-eclampsia	Alliance of Genome Resources
DOID:12554	hemolytic-uremic syndrome	Alliance of Genome Resources
DOID:2377	multiple sclerosis	Alliance of Genome Resources
DOID:2773	contact dermatitis	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 28** of 28 in total

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Species	Gene ID	Orthologous MAtrix
Chlorocebus sabaeus	103230174	CHLSB11987
Nannospalax galili	103727021	NANGA04357
Callithrix jacchus	103789310	CALJA16839
Rhinopithecus roxellana	104664177	RHIRO12253
Macaca nemestrina	105484874	MACNE03115
Mandrillus leucophaeus	105536435	MANLE10370
Cercocebus atys	105577091	CERAT13141
Rhinopithecus bieti	108539537	RHIBE16777

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements