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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
MYCN proto-oncogene, bHLH transcription factor
Summary
- Gene Symbol
-
- MYCN
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Coiled coil
- DNA-binding
- Disease variant
- Nucleus
- Phosphoprotein
- Proteomics identification
- Proto-oncogene
- Reference proteome
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9H224 |
|
| A0A1W2PPD9 |
|
| P04198 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of miRNA transcription | ||
| regulation of transcription by RNA polymerase II | ||
| positive regulation of gene expression | ||
| negative regulation of gene expression | ||
| positive regulation of transcription, DNA-templated |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase binding | ||
| protein binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA binding | ||
| protein dimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Myc
- Functional Category
-
- I: Lipid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| protein dimerization activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060464 | Feingold syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 107601291 | SINGR09349 | |||
| 108260986 | ICTPU25657 | |||
| 109053507 | CYPCA103795 | |||
| 109311636 | CROPO09663 | |||
| 110194881 | PHACI22371 | |||
| 113455246 | PSETE03324 | |||
| 114593814 | PODMU17786 | |||
| 115038174 | ECHNA32072 | |||
| 115175070 | SALTR53167 | |||
| 115195561 | SALTR27813 |
