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5'-nucleotidase ecto
Summary
- Gene Symbol
-
- NT5E
- Aliases
-
- CALJA
- CD73
- eN
- eNT
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- GPI-anchor
- Hydrolase
- Metal-binding
- Nucleotide-binding
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to ATP | ||
| leukocyte cell-cell adhesion | ||
| ADP catabolic process | ||
| AMP catabolic process | ||
| ATP metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
catabolic process [inference]
cellular catabolic process [inference]
organic substance catabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
cellular biosynthetic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
heterocycle catabolic process [inference]
primary metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
carbohydrate derivative metabolic process [inference]
organic cyclic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
organic cyclic compound catabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
cellular biosynthetic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
nucleobase-containing compound catabolic process [inference]
nucleobase-containing small molecule metabolic process [inference]
heterocycle catabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| external side of plasma membrane | ||
| cell surface | ||
| plasma membrane | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| XMP 5'-nucleosidase activity | ||
| thymidylate 5'-phosphatase activity | ||
| zinc ion binding | ||
| IMP 5'-nucleotidase activity | ||
| protein binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060857 | septooptic dysplasia | |
| DOID:0060870 | isolated growth hormone deficiency | |
| DOID:0060872 | isolated growth hormone deficiency type II | |
| DOID:0060873 | isolated growth hormone deficiency type IA | |
| DOID:0060874 | isolated growth hormone deficiency type IB | |
| DOID:0060875 | isolated growth hormone deficiency type III | |
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 | |
| DOID:0080038 | pycnodysostosis |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001717 | Coronary artery calcification |
| HP:0003207 | Arterial calcification |
| HP:0004417 | Intermittent claudication |
| HP:0005116 | Arterial tortuosity |
| HP:0005645 | Intervertebral disk calcification |
| HP:0011025 | Abnormal cardiovascular system physiology |
| HP:0011986 | Ectopic ossification |
| HP:0012101 | Decreased serum creatinine |
| Disease ID | Disease Name |
|---|---|
| ORPHA:289601 |
|
| OMIM:211800 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105998218 | DIPOR19840 | ||
| 100759374 | CRIGR00936 | ||
| 23959 | MGI:99782 | MOUSE61491 | |
| 58813 | RGD:61956 | RATNO41307 | |
| 100725593 | CAVPO07309 | ||
| 101707419 | HETGA06163 | ||
| 107104329 | CYPVA30660 | ||
| 114037845 | VOMUR08822 | ||
| 113898394 | BOBOX27557 | ||
| 105862229 | MICMU10694 |
