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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Summary
- Gene Symbol
-
- PIK3CG
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Angiogenesis
- Cell membrane
- Chemotaxis
- Cytoplasm
- Disease variant
- Endocytosis
- Immunity
- Inflammatory response
- Kinase
- Lipid metabolism
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| phospholipase C-activating G protein-coupled receptor signaling pathway | ||
| phosphorylation | ||
| negative regulation of triglyceride catabolic process | ||
| dendritic cell chemotaxis |
|
|
| phosphatidylinositol 3-kinase/protein kinase B signal transduction |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| ephrin receptor binding | ||
| 1-phosphatidylinositol-3-kinase activity | ||
| protein serine/threonine kinase activity | ||
| protein serine kinase activity |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3068 | glioblastoma | |
| DOID:3069 | malignant astrocytoma | |
| DOID:3070 | high grade glioma | |
| DOID:3071 | gliosarcoma | |
| DOID:3074 | giant cell glioblastoma | |
| DOID:3078 | anaplastic astrocytoma | |
| DOID:3079 | childhood astrocytic tumor | |
| DOID:3083 | chronic obstructive pulmonary disease | |
| DOID:3095 | germ cell and embryonal cancer | |
| DOID:3112 | papillary adenocarcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000010 | Recurrent urinary tract infections |
| HP:0000403 | Recurrent otitis media |
| HP:0000964 | Eczematoid dermatitis |
| HP:0001252 | Hypotonia |
| HP:0001433 | Hepatosplenomegaly |
| HP:0001581 | Recurrent skin infections |
| HP:0001742 | Nasal congestion |
| HP:0001744 | Splenomegaly |
| HP:0001873 | Thrombocytopenia |
| Disease ID | Disease Name |
|---|---|
| OMIM:619802 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP000468
- Gene Name
- phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101096215 | FELCA03042 | ||
| 122206263 | PANLE22381 | ||
| 101336571 | TURTR01860 | ||
| 118900854 | BALMU12651 | ||
| 100673566 | LOXAF17782 | ||
| 100050532 | HORSE33500 | ||
| 396979 | PIGXX36424 | ||
| 530001 | BOVIN27946 | ||
| 102173256 | CAPHI23797 | ||
| 101102896 | SHEEP15440 |
