phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

Summary
Gene Symbol
  • PIK3CG
Organism
Homo sapiens (human)
External Links
NCBI Gene
5294
HGNC
8978
KEGG Gene ID
hsa:5294
PubChem
5294
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Angiogenesis
  • Cell membrane
  • Chemotaxis
  • Cytoplasm
  • Disease variant
  • Endocytosis
  • Immunity
  • Inflammatory response
  • Kinase
  • Lipid metabolism
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
Proteins
Displaying all 2 entries
UniProt Protein Name
P48736
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
  • Phosphoinositide-3-kinase catalytic gamma polypeptide
  • Serine/threonine protein kinase PIK3CG
  • p120-PI3K
A8K9G9
Gene Ontology (GO)
Displaying entry 41 - 41 of 41 in total
GO Term Evidence Code PMID
negative regulation of fibroblast apoptotic process
GO Hierarchy
GO Hierarchy
KEGG BRITE Database
Orthology
K21289
Name
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
References
Disease
Disease Ontology
Displaying entries 101 - 110 of 948 in total
DO ID Disease Name Source
DOID:0060895 Parkinson's disease 4
DOID:0060896 Parkinson's disease 23
DOID:0060901 lymphoplasmacytic lymphoma
DOID:0070189 X-linked spermatogenic failure 1
DOID:0070314 obstructive nephropathy
DOID:0070324 systemic Epstein-Barr virus positive T-cell lymphoma of childhood
DOID:0070329 mitochondrial DNA depletion syndrome
DOID:0080001 bone disease
DOID:0080144 childhood acute lymphocytic leukemia
DOID:0080145 childhood T-cell acute lymphoblastic leukemia
The Human Phenotype Ontology
Displaying entries 11 - 20 of 36 in total
HPO ID HPO Term
HP:0001880 Eosinophilia
HP:0001888 Lymphopenia
HP:0001890 Autoimmune hemolytic anemia
HP:0001904 Neutropenia in presence of anti-neutropil antibodies
HP:0001945 Fever
HP:0002014 Diarrhea
HP:0002027 Abdominal pain
HP:0002155 Hypertriglyceridemia
HP:0002583 Colitis
HP:0002716 Lymphadenopathy
Displaying 1 entry
Disease ID Disease Name
OMIM:619802
  • immunodeficiency 97 with autoinflammation
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP000468
Gene Name
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024