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phosphomannomutase 1

Summary

Gene Symbol

PMM1

Aliases

Sec53
brain glucose-1,6-bisphosphatase

Organism

Homo sapiens (human)

External Links

NCBI Gene

5372

HGNC

9114

KEGG Gene ID

hsa:5372

PubChem

5372

Alliance of Genome Resources

HGNC:9114

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Isomerase
Magnesium
Metal-binding
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q92871	PMMH-22

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IBA
mannose metabolic process	IBA IDA	16540464
cellular response to leukemia inhibitory factor	IEA
GDP-mannose biosynthetic process	IEA TAS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

mannose metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

GDP-mannose metabolic process [inference]

GDP-mannose biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleotide-sugar biosynthetic process [inference]

GDP-mannose biosynthetic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IBA IDA TAS
neuronal cell body	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

cell body [inference]

neuronal cell body

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
protein binding	IPI	16189514 25416956 32296183
phosphomannomutase activity	IBA IDA TAS	16540464

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity [inference]

intramolecular transferase activity [inference]

intramolecular phosphotransferase activity [inference]

phosphomannomutase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K17497

Name

phosphomannomutase [EC:5.4.2.8]

References

16540464

Rhea

RHEA:11140

α-D-mannose 1-phosphate

D-mannose 6-phosphate

Enzyme

5.4.2.8

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050570	congenital disorder of glycosylation type I	DisGeNET Alliance of Genome Resources
DOID:0080552	congenital disorder of glycosylation Ia	DisGeNET Alliance of Genome Resources
DOID:2237	hepatitis	DisGeNET

Ortholog

Displaying entries **11 - 20** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Oreochromis niloticus	100699648		ORENI56268
Haplochromis burtoni	102305061		HAPBU28799
Astatotilapia calliptera	113021156		ASTCA31049
Sparus aurata	115576190		SPAAU00868
Xenopus laevis	447608	Xenbase:XB-GENE-974469
Xenopus tropicalis	100216238	Xenbase:XB-GENE-998969
Crocodylus porosus	109316736		CROPO05921
Pseudonaja textilis	113436739		PSETE00014
Meleagris gallopavo	100546782		MELGA00566
Serinus canaria	103813300		SERCA05860

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements