GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein kinase activity	TAS	10570282
protein serine/threonine kinase activity	TAS
MAP kinase kinase activity	IDA	28166211 8388392
MAP kinase kinase activity	IBA
protein serine/threonine/tyrosine kinase activity	TAS	19565474

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

MAP kinase kinase activity

JUN kinase kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

MAP kinase kinase activity

JUN kinase kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

MAP kinase kinase activity

JUN kinase kinase activity

binding [inference]

protein binding

scaffold protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity [inference]

MAP-kinase scaffold activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dual specificity mitogen-activated

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
protein phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0111462	cardiofaciocutaneous syndrome 3	Alliance of Genome Resources
DOID:3070	high grade glioma	Alliance of Genome Resources
DOID:4074	pancreatic adenocarcinoma	Alliance of Genome Resources
DOID:4253	melorheostosis	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:4906	small intestine adenocarcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **71 - 78** of 78 in total

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Species	Gene ID	Orthologous MAtrix
Strigops habroptila	115612648	STRHB22986
Corvus moneduloides	116450331	CORMO02575
Chelonoidis abingdonii	116816669	CHEAB03776
Rhinolophus ferrumequinum	117022968	RHIFE31470
Scophthalmus maximus	118314932	SCOMX00707
Balaenoptera musculus	118891063	BALMU29491
Panthera leo	122221892	PANLE20019
Ictalurus punctatus	124627985	ICTPU28205

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Annotation

OrthoDB (Group)

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Acknowledgements