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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sphingosine kinase 2
Summary
- Gene Symbol
-
- SPHK2
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of reactive oxygen species biosynthetic process | ||
| sphingolipid biosynthetic process |
|
GO Hierarchy
- regulation of reactive oxygen species biosynthetic process
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| mitochondrial inner membrane | ||
| nucleosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| small GTPase binding |
|
|
| D-erythro-sphingosine kinase activity | ||
| histone binding | ||
| lipid kinase activity |
|
|
| sphinganine kinase activity |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4947 | cholangiocarcinoma | |
| DOID:4989 | pancreatitis | |
| DOID:5076 | mixed glioma | |
| DOID:5077 | subependymal giant cell astrocytoma | |
| DOID:5082 | liver cirrhosis | |
| DOID:5162 | arteriolosclerosis | |
| DOID:5199 | ureteral obstruction | |
| DOID:552 | pneumonia | |
| DOID:5604 | adult acute lymphocytic leukemia | |
| DOID:5672 | large intestine cancer |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001959
- Gene Name
- sphingosine kinase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115567369 | SPAAU59856 | ||
| 108696679 | Xenbase:XB-GENE-17346103 | ||
| 108697745 | Xenbase:XB-GENE-6487776 | ||
| 100494664 | Xenbase:XB-GENE-991354 | ||
| 100087297 | ORNAN00811 | ||
| 100387720 | CALJA24447 | ||
| 105595245 | CERAT28494 | ||
| 718088 | MACMU18024 | ||
| 105478648 | MACNE39731 | ||
| 105539178 | MANLE32656 |
