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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sphingosine kinase 2
Summary
- Gene Symbol
-
- SPHK2
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of reactive oxygen species biosynthetic process | ||
| sphingolipid biosynthetic process |
|
GO Hierarchy
- regulation of reactive oxygen species biosynthetic process
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| mitochondrial inner membrane | ||
| nucleosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| small GTPase binding |
|
|
| D-erythro-sphingosine kinase activity | ||
| histone binding | ||
| lipid kinase activity |
|
|
| sphinganine kinase activity |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12849 | autistic disorder | |
| DOID:12858 | Huntington's disease | |
| DOID:1287 | cardiovascular system disease | |
| DOID:1289 | neurodegenerative disease | |
| DOID:1324 | lung cancer | |
| DOID:1325 | bronchus cancer | |
| DOID:14018 | alcoholic liver cirrhosis | |
| DOID:1443 | cerebral degeneration | |
| DOID:14525 | Reye syndrome | |
| DOID:1485 | cystic fibrosis |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001959
- Gene Name
- sphingosine kinase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 103657238 | URSMA25483 | ||
| 114041882 | VOMUR30686 | ||
| 113876247 | BOBOX11583 | ||
| 105865659 | MICMU03982 | ||
| 101078125 | TAKRU46299 | ||
| 102007376 | CHILA24052 | ||
| 105722532 | AOTNA32423 | ||
| 101044895 | SAIBB33166 | ||
| 108410635 | PYGNA31064 | ||
| 101972510 | ICTTR05971 |
