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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sphingosine kinase 2
Summary
- Gene Symbol
-
- SPHK2
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of reactive oxygen species biosynthetic process | ||
| sphingolipid biosynthetic process |
|
GO Hierarchy
- regulation of reactive oxygen species biosynthetic process
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| mitochondrial inner membrane | ||
| nucleosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| small GTPase binding |
|
|
| D-erythro-sphingosine kinase activity | ||
| histone binding | ||
| lipid kinase activity |
|
|
| sphinganine kinase activity |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2349 | arteriosclerosis | |
| DOID:235 | colonic benign neoplasm | |
| DOID:2377 | multiple sclerosis | |
| DOID:2531 | hematologic cancer | |
| DOID:2703 | synovitis | |
| DOID:2797 | idiopathic interstitial pneumonia | |
| DOID:2913 | acute pancreatitis | |
| DOID:2914 | immune system disease | |
| DOID:305 | carcinoma | |
| DOID:3068 | glioblastoma |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001959
- Gene Name
- sphingosine kinase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100054066 | HORSE00996 | ||
| 100738292 | PIGXX28190 | ||
| 102184187 | CAPHI09354 | ||
| 101106964 | SHEEP05630 | ||
| 105994375 | DIPOR18944 | ||
| 56632 | MGI:1861380 | MOUSE55098 | |
| 308589 | RGD:1307757 | RATNO16993 | |
| 100730608 | CAVPO19324 | ||
| 101565211 | OCTDE25146 | ||
| 101720879 | HETGA20946 |
