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ribosomal protein L3

Summary

Gene Symbol

RPL3

Organism

Homo sapiens (human)

External Links

NCBI Gene

6122

PubChem

6122

Alliance of Genome Resources

HGNC:10332

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Direct protein sequencing
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
Ribosomal protein
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B3KS36	60S ribosomal protein L3
P39023	60S ribosomal protein L3 HIV-1 TAR RNA-binding protein B
Q96QL0	60S ribosomal protein L3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
translation	IBA NAS	12962325
cellular response to interleukin-4	IEA
cytoplasmic translation	IC	23636399

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

primary metabolic process [inference]

protein metabolic process [inference]

cytoplasmic translation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to interleukin-4 [inference]

cellular response to interleukin-4

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
focal adhesion	HDA	21423176
protein-containing complex	IDA	23349634
cytosolic ribosome	IDA	23636399 32669547
nucleus	HDA	21630459
cytosol	IDA TAS

GO Hierarchy

cellular component

protein-containing complex

ribonucleoprotein complex [inference]

ribosomal subunit [inference]

large ribosomal subunit [inference]

cytosolic large ribosomal subunit

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

ribosome [inference]

cytosolic ribosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

ribosome [inference]

cytosolic ribosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	23349634 24965446 25854864 26100019 32814053
structural constituent of ribosome	IBA IDA NAS	12962325 23636399 32669547
RNA binding	HDA IBA	22658674 22681889

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of ribosome

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ribosomal protein

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
Large ribosomal subunit protein uL3, archaeal/eukaryotic-type
Large ribosomal subunit protein uL3, conserved site
Large ribosomal subunit protein uL3
Ribosomal protein L3, domain 3, archaeal-type superfamily
Translation protein, beta-barrel domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060479	Shwachman-Diamond syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **91 - 95** of 95 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Balaenoptera musculus	118902319			BALMU04418
Panthera leo	122225143			PANLE17069
Ursus americanus	123780773			URSAM02297
Callithrix jacchus	128928036			CALJA20423
Pongo pygmaeus	129023024	9600_0:005179

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024