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roundabout guidance receptor 3

Summary

Gene Symbol

ROBO3

Organism

Homo sapiens (human)

External Links

NCBI Gene

64221

PubChem

64221

Alliance of Genome Resources

HGNC:13433

Annotation

Keyword

3D-structure
Alternative splicing
Chemotaxis
Developmental protein
Differentiation
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Neurogenesis
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96MS0	Roundabout-like protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
chemotaxis	IEA
positive regulation of axon guidance	IEA
dendrite self-avoidance	IBA
axon midline choice point recognition	ISS
homophilic cell adhesion via plasma membrane adhesion molecules	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell recognition [inference]

neuron recognition [inference]

axon choice point recognition [inference]

axon midline choice point recognition

dendrite self-avoidance

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

locomotion [inference]

taxis [inference]

chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of axon guidance [inference]

positive regulation of axon guidance

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	NAS	15105459
plasma membrane	IBA TAS
axon	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	26586761 32198364
cell-cell adhesion mediator activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

roundabout

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
InterPro
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060475	myoclonic-atonic epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 47 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Saimiri boliviensis boliviensis	101049023		SAIBB06297
Felis catus	101084731		FELCA24431
Ovis aries	101117204		SHEEP10924
Gorilla gorilla gorilla	101151496	9595_0:003180	GORGO02607
Jaculus jaculus	101595019		JACJA22705
Mustela putorius furo	101686543		MUSPF14629
Chinchilla lanigera	102015822		CHILA03559
Chlorocebus sabaeus	103248751		CHLSB01141
Nannospalax galili	103735682		NANGA11794
Rhinopithecus roxellana	104679134		RHIRO39130

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements