Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
toll like receptor 2
Summary
- Gene Symbol
-
- TLR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Isopeptide bond
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| O60603 |
|
| A0A0S2Z4S4 |
|
| B3KWR9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to triacyl bacterial lipopeptide | ||
| positive regulation of nitric-oxide synthase biosynthetic process | ||
| negative regulation of cell population proliferation | ||
| positive regulation of NF-kappaB transcription factor activity | ||
| nitric oxide metabolic process |
GO Hierarchy
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
biological process
immune system process [inference]
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to external stimulus [inference]
response to biotic stimulus [inference]
response to chemical [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to cytokine stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| receptor complex | ||
| cell body | ||
| cytoplasm | ||
| Toll-like receptor 1-Toll-like receptor 2 protein complex | ||
| cell surface |
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane signaling receptor activity | ||
| NAD+ nucleotidase, cyclic ADP-ribose generating | ||
| amyloid-beta binding | ||
| lipopolysaccharide binding | ||
| Toll-like receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2957 | pulmonary tuberculosis | |
| DOID:3178 | skin papilloma | |
| DOID:3310 | atopic dermatitis | |
| DOID:399 | tuberculosis | |
| DOID:4481 | allergic rhinitis | |
| DOID:4483 | rhinitis | |
| DOID:4677 | keratitis | |
| DOID:4989 | pancreatitis | |
| DOID:5614 | eye disease | |
| DOID:6543 | acne |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 123793207 | URSAM03844 | ||
| 101681595 | MUSPF05009 | ||
| 493797 | FELCA10249 | ||
| 122217778 | PANLE27407 | ||
| 101338049 | TURTR13882 | ||
| 118896009 | BALMU27833 | ||
| 100654442 | LOXAF06918 | ||
| 100009701 | HORSE27888 | ||
| 396623 | PIGXX33967 | ||
| 281534 | BOVIN09038 |
