phospholipase A2 group VI
| UniProt | Protein Name |
|---|---|
| O60733 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| cardiolipin acyl-chain remodeling | ||
| cardiolipin acyl-chain remodeling | ||
| Fc-gamma receptor signaling pathway involved in phagocytosis | ||
| phosphatidylethanolamine catabolic process | ||
| platelet activating factor metabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| mitochondrion | ||
| mitochondrion | ||
| cytosol | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrolase activity | ||
| serine hydrolase activity | ||
| identical protein binding | ||
| calcium-independent phospholipase A2 activity | ||
| calcium-independent phospholipase A2 activity |
| Gene Ontology |
|---|
| calcium-independent phospholipase A2 activity |
| cardiolipin acyl-chain remodeling |
| hydrolase activity |
| lipid metabolic process |
| positive regulation of ceramide biosynthetic process |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060900 | Parkinson's disease 14 | |
| DOID:0090056 | dystonia 12 | |
| DOID:0110735 | neurodegeneration with brain iron accumulation 2a | |
| DOID:0110736 | neurodegeneration with brain iron accumulation 2b | |
| DOID:14330 | Parkinson's disease | |
| DOID:2367 | neuroaxonal dystrophy |
| HPO ID | HPO Term |
|---|---|
| HP:0000736 | Short attention span |
| HP:0000746 | Delusion |
| HP:0000750 | Delayed speech and language development |
| HP:0000751 | Personality changes |
| HP:0000752 | Hyperactivity |
| HP:0000762 | Decreased nerve conduction velocity |
| HP:0001249 | Intellectual disability |
| HP:0001250 | Seizure |
| HP:0001251 | Ataxia |
| HP:0001252 | Hypotonia |
| Disease ID | Disease Name |
|---|---|
| OMIM:610217 |
|
| ORPHA:35069 |
|
| ORPHA:199351 |
|
| OMIM:256600 |
|
| OMIM:612953 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 8398 | Xenbase:XB-GENE-920447 | ||
| 53357 | Xenbase:XB-GENE-920447 | MOUSE16942 | |
| 360426 | RATNO38024 | ||
| 406370 | DANRE23128 | ||
| 470208 | PANTR26555 | ||
| 481256 | CANLF01620 | ||
| 535381 | BOVIN30650 | ||
| 100016178 | MONDO00647 | ||
| 100090638 | ORNAN06146 | ||
| 100222459 | TAEGU09100 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025