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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diacylglycerol O-acyltransferase 2
Summary
- Gene Symbol
-
- DGAT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acyltransferase
- Alternative splicing
- Cytoplasm
- Endoplasmic reticulum
- Glycerol metabolism
- Lipid biosynthesis
- Lipid droplet
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q96PD7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| diacylglycerol metabolic process | ||
| cholesterol homeostasis | ||
| lipid storage | ||
| retinol metabolic process | ||
| glycerol metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| cytosol | ||
| lipid droplet | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein homodimerization activity | ||
| diacylglycerol O-acyltransferase activity | ||
| 2-acylglycerol O-acyltransferase activity | ||
| protein binding | ||
| retinol O-fatty-acyltransferase activity |
GO Hierarchy
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110212 | Charcot-Marie-Tooth disease X-linked recessive 4 | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10595 | Charcot-Marie-Tooth disease | |
| DOID:10787 | premature menopause | |
| DOID:13580 | cholestasis | |
| DOID:1389 | polyneuropathy | |
| DOID:162 | cancer | |
| DOID:1883 | hepatitis C | |
| DOID:2043 | hepatitis B |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP005085
- Gene Name
- diacylglycerol O-acyltransferase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101589933 | OCTDE10160 | ||
| 101698712 | HETGA04664 | ||
| 100011089 | MONDO24148 | ||
| 102453357 | PELSI08472 | ||
| 103678126 | URSMA22252 | ||
| 114032840 | VOMUR14548 | ||
| 105860306 | MICMU12515 | ||
| 100955161 | OTOGA18984 | ||
| 101079383 | TAKRU12618 | ||
| 102022183 | CHILA03769 |
