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Gremlin-1

Summary

UniProt ID

O35793

Gene Symbol

Grem1
Cktsf1b1
Drm

Organism

Rattus norvegicus (Norway rat)

External Links

Annotation

Keyword

Cytokine
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **31 - 40** of 43 in total

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GO Term
negative regulation of BMP signaling pathway
determination of dorsal identity
negative regulation of DNA-templated transcription
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
cell migration involved in sprouting angiogenesis
positive regulation of receptor internalization
proximal/distal pattern formation
positive regulation of non-canonical NF-kappaB signal transduction
sequestering of BMP from receptor via BMP binding

Displaying **all 3** entries
GO Term
extracellular region
extracellular space
cell surface

Displaying **all 6** entries
GO Term
protein homodimerization activity
cytokine activity
receptor ligand activity
BMP binding
transmembrane receptor protein tyrosine kinase activator activity
vascular endothelial growth factor receptor 2 binding

Annotation information from UniProt.

Sequence

MNRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPPQPGSRTRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites