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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibrinogen alpha chain
Summary
- UniProt ID
- P02671
- Gene Symbol
-
- FGA
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011303
- GlyConnect
- GlyGen
- P02671
- PubChem
- P02671
- The Human Metabolome Database
- HMDBP13512
- RaftProt
- P02671
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Amyloid
- Amyloidosis
- Blood coagulation
- Calcium
- Coiled coil
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Innate immunity
- Isopeptide bond
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| GO Term |
|---|
| extracellular region |
| fibrinogen complex |
| extracellular space |
| plasma membrane |
| collagen-containing extracellular matrix |
| extracellular exosome |
| extracellular vesicle |
| platelet alpha granule lumen |
| platelet alpha granule |
| endoplasmic reticulum |
| GO Term |
|---|
| signaling receptor binding |
| metal ion binding |
| structural molecule activity |
| extracellular matrix structural constituent |
Sequence
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 562 |
|
|||
| 582 |
|
|||
| 586 |
|
|||
| 603 |
|
|||
| 616 |
|
|||
| 684 |
|
|
||
| 686 | N-linked (GlcNAc...) asparagine | |||
|
|
G43417UB
G29068FM
G57321FI
G45395BF
G00912UN
G78790NZ
G25418HZ
G39619TI
G59626AS
G62765YT
G48414YA
G84467IZ
G06356OH
G75850OP
G91365ZQ
G36191CD
G50045TK
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Paradoxical activation of RAF signaling by kinase inactive BRAF | Homo sapiens |
| Platelet degranulation | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| Regulation of TLR by endogenous ligand | Homo sapiens |
| Signaling by BRAF and RAF1 fusions | Homo sapiens |
| Signaling by RAF1 mutants | Homo sapiens |
| Signaling by high-kinase activity BRAF mutants | Homo sapiens |
| Signaling by moderate kinase activity BRAF mutants | Homo sapiens |
| Signaling downstream of RAS mutants | Homo sapiens |
