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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Intercellular adhesion molecule 1
Summary
- UniProt ID
- P05362
- Gene Symbol
-
- ICAM1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011393
- GlyConnect
- GlyGen
- P05362
- PubChem
- P05362
- The Human Metabolome Database
- HMDBP02089
- The O-GlcNAc Database
- P05362
- RaftProt
- P05362
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Host cell receptor for virus entry
- Host-virus interaction
- Immunoglobulin domain
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| transmembrane signaling receptor activity |
| signaling receptor activity |
| virus receptor activity |
| integrin binding |
Sequence
MAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPRGGSVLVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQSTAKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKREPAVGEPAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATPPQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASVSVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEAHPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRVLYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRDLEGTYLCRARSTQGEVTRKVTVNVLSPRYEIVIITVVAAAVIMGTAGLSTYLYNRQRKIKKYRLQQAQKGTPMKPNTQATPP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 57 |
|
|||
| 62 |
|
|||
| 95 |
|
|
||
| 130 | N-linked (GlcNAc...) asparagine |
|
||
| 145 | N-linked (GlcNAc...) (complex) asparagine | |||
| 183 | N-linked (GlcNAc...) asparagine | |||
| 202 | N-linked (GlcNAc...) asparagine | |||
| 267 | N-linked (GlcNAc...) asparagine |
|
||
| 296 | N-linked (GlcNAc...) asparagine |
|
||
| 385 | N-linked (GlcNAc...) asparagine |
G57321FI
G05962QB
G30740WO
G69521XL
G57776ZS
G68490OW
G86880BF
G27947YN
G85282JO
G79666IR
G45395BF
G40926MX
G37818NZ
G93718GY
G16125XL
G80479JV
G07246CJ
G78787DI
G80920RR
G62765YT
G53075ES
G94665LC
G30221QT
G81637OR
G71463BG
G65414LI
G50856PC
G82443XX
G95046LV
G32788FZ
G01160VV
G60967DT
G80669SJ
G39471UU
G45526EA
G15169WU
G70232NH
G55132BD
G70888PK
G06247RL
G35541EV
G13131HA
G75568BH
G80075MS
G29545VG
G60834IK
G28622IK
G90382BL
G30970QQ
G40206WX
G20528HD
G87123QX
G92135MA
G40834TG
G02528FI
G10819WX
G14972EH
G43223CG
G08918WF
G00912UN
G70441OD
G76295SF
G04657PL
G27058EU
G24528MX
G83460ZZ
G60033FS
G41071NU
G01650EU
G01485JJ
G59924QI
G37399XV
G85269DF
G59324HL
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110756 | type 1 diabetes mellitus 19 | |
| DOID:0110757 | type 1 diabetes mellitus 20 | |
| DOID:0110758 | type 1 diabetes mellitus 21 | |
| DOID:0110759 | type 1 diabetes mellitus 22 | |
| DOID:0110760 | type 1 diabetes mellitus 23 | |
| DOID:0110761 | type 1 diabetes mellitus 24 | |
| DOID:0110845 | xeroderma pigmentosum group D | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111029 | hemochromatosis type 1 | |
| DOID:0111095 | Fanconi anemia complementation group A |
